(S)-1-Fmoc-4-oxopiperidine-2-carboxylic acid
(S)-1-Fmoc-4-oxopiperidine-2-carboxylic acid (CAS: 1221793-43-6) is a chiral building block with the molecular formula C21H19NO5 and a molecular weight of 365.38. This compound, also known as Fmoc-L-Homopro(4-oxo)-OH, is valuable in asymmetric synthesis and chemical research. Its piperidine structure and functional groups make it a versatile intermediate for constructing more complex heterocyclic molecules. It is typically stored at 2-8°C to maintain its integrity.
- IUPAC
- (S)-1-Fmoc-4-oxohomoproline,Fmoc-L-Homopro(4-oxo)-OH
- Synonyms
- (S)-1-Fmoc-4-oxohomoprolineFmoc-L-Homopro(4-oxo)-OH

Asymmetric Synthesis
Serves as a chiral building block for stereoselective synthesis of complex organic molecules. Its defined stereochemistry is crucial for creating enantiomerically pure compounds.
Pharmaceutical Intermediates
Utilised in the development of novel pharmaceutical agents, particularly where a piperidine core with specific functionalisation is required. Aids in the construction of potential drug candidates.
Heterocyclic Chemistry
Acts as a key intermediate for the synthesis of diverse heterocyclic compounds. The oxopiperidine moiety offers reactive sites for further chemical modification and ring system elaboration.
Research and Development
Employed in academic and industrial research laboratories for exploring new synthetic methodologies and developing novel chemical entities. Facilitates fundamental research in organic chemistry.
| Molecular weight | 365.38 |
|---|---|
| Empirical formula | C21H19NO5 |
| Storage temperature | 2-8°C |
| Melting point | 228-233 °C |

Hazard statements
- H400Very toxic to aquatic life
Precautionary statements
- P273Avoid release to the environment
| Transport (UN / ADR) | UN 3077 9 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | N |
| Risk statements (R) | 50 |
| Safety statements (S) | 61 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-Fmoc-4-oxopiperidine-2-carboxylic acid used for?
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(S)-1-Fmoc-4-oxopiperidine-2-carboxylic acid is used in asymmetric synthesis, pharmaceutical intermediate development, heterocyclic chemistry, and general research and development in organic synthesis.
What is the CAS number and molecular formula?
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The CAS number is 1221793-43-6 and the molecular formula is C21H19NO5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical for research purposes. Purity and grade information are available on the product's Certificate of Analysis. It is not supplied as USP, BP, EP, or pharmaceutical grade.
How should (S)-1-Fmoc-4-oxopiperidine-2-carboxylic acid be handled?
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This compound is classified as hazardous to the aquatic environment (H400) and is labelled with a Warning signal word. Handle with appropriate personal protective equipment, avoid release into the environment (P273), and store at 2-8°C. Consult the Safety Data Sheet (SDS) for detailed handling procedures.
Is this chemical a controlled substance?
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Based on the provided data, there is no indication that (S)-1-Fmoc-4-oxopiperidine-2-carboxylic acid is a controlled substance.
How is this product packed and shipped globally?
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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging for international shipment in compliance with transport regulations such as UN 3077, 9 / PGIII.
How can I request a sample or quote?
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To request a sample or a quotation for (S)-1-Fmoc-4-oxopiperidine-2-carboxylic acid, please contact the Tech Serve Solutions sales team via the website or listed contact details.
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