(S)-1-Phenyl-2-propyn-1-ol
(S)-1-Phenyl-2-propyn-1-ol (CAS 64599-56-0, C9H8O) is a chiral alcohol with a molecular weight of 132.16 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in asymmetric synthesis due to its defined stereochemistry. Its structure, featuring both an alkynyl and a secondary alcohol group, makes it a versatile intermediate for creating complex molecules.
- IUPAC
- (S)-α-Ethynylbenzyl alcohol
- Synonyms
- (S)-α-Ethynylbenzyl alcohol
Chiral Building Block
(S)-1-Phenyl-2-propyn-1-ol is a key chiral intermediate used in the synthesis of enantiomerically pure compounds. Its specific stereochemistry is crucial for building complex molecular architectures in pharmaceuticals and fine chemicals.
Asymmetric Synthesis
This compound is instrumental in asymmetric synthesis, allowing for the stereoselective introduction of functional groups. It facilitates the creation of target molecules with high optical purity, essential in modern drug discovery.
Organic Synthesis Intermediate
As an organic building block, (S)-1-Phenyl-2-propyn-1-ol can participate in a variety of reactions. Its propargyl alcohol moiety can undergo transformations like additions, oxidations, or reductions, leading to diverse chemical entities.
| Molecular weight | 132.16 |
|---|---|
| Empirical formula | C9H8O |
| Assay | ≥99.0% (sum of enantiomers, GC) |
| Density | 1.067 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.551 |
| Optical activity | [α]20/D +28±2°, c = 3.2% in chloroform |
| Optical purity | enantiomeric ratio: ≥98:2 (HPLC) |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 99 °C / 210.2 °F |
| Transport (UN / ADR) | UN 2810 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 26-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-Phenyl-2-propyn-1-ol used for?
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It is primarily used as a chiral building block and intermediate in asymmetric and general organic synthesis, particularly in the development of pharmaceuticals and fine chemicals.
What are the CAS number and formula for (S)-1-Phenyl-2-propyn-1-ol?
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The CAS number is 64599-56-0, and the empirical formula is C9H8O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (S)-1-Phenyl-2-propyn-1-ol with an assay of ≥99.0% (sum of enantiomers, GC). We do not represent this product as USP, BP, or EP grade.
How should (S)-1-Phenyl-2-propyn-1-ol be handled?
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This compound is harmful if swallowed (H302). Appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection (e.g., type ABEK respirator filter), should be used. Handle in a well-ventilated area.
How is (S)-1-Phenyl-2-propyn-1-ol exported and shipped?
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(S)-1-Phenyl-2-propyn-1-ol is classified under UN 2810, Hazard Class 6.1, Packing Group III. Tech Serve Solutions expertly handles all export documentation and shipping requirements for this material.
How can I request a sample or quote for (S)-1-Phenyl-2-propyn-1-ol?
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Please contact our sales team via the website or direct email to request a quotation or sample for (S)-1-Phenyl-2-propyn-1-ol.
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