(S)-1-[(1-Methyl-2-pyrrolidinyl)methyl]piperidine

CAS 84466-85-3C11H22N2Chemical Synthesis

(S)-1-[(1-Methyl-2-pyrrolidinyl)methyl]piperidine (CAS 84466-85-3), with the molecular formula C11H22N2 and a molecular weight of 182.31 g/mol, is a valuable chiral building block. This compound serves as an effective chiral ligand in catalytic asymmetric synthesis, particularly noted for its utility in asymmetric aldol reactions. Its precise stereochemistry makes it instrumental in controlling enantioselectivity in complex chemical transformations.

IUPAC: (S)-1-Methyl-2-(piperidinomethyl)pyrrolidine

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(S)-1-[(1-Methyl-2-pyrrolidinyl)methyl]piperidine (C11H22N2) — chemical structure, CAS 84466-85-3; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksPyrrolidines

01 /Applications

Chiral Ligand in Asymmetric Synthesis

This compound functions as a chiral ligand, enabling stereoselective control in various catalytic asymmetric reactions. It has been specifically noted for its application in Mukaiyama aldol reactions, facilitating the formation of enantiomerically enriched products.

Heterocyclic Building Block

Possessing both pyrrolidine and piperidine ring systems, this molecule is a versatile heterocyclic building block. It can be incorporated into more complex molecular architectures for applications in medicinal chemistry and materials science.

Asymmetric Aldol Reactions

A key application involves its use as a chiral auxiliary or ligand in asymmetric aldol reactions. This allows for the stereoselective synthesis of beta-hydroxy carbonyl compounds, which are important intermediates in organic synthesis.

02 /Properties

Molecular weight	182.31
Empirical formula	C11H22N2
Assay	97%
Boiling point	121-123 °C/22 mmHg(lit.)
Density	0.909 g/mL at 25 °C(lit.)
Refractive index	n20/D 1.478(lit.)
Optical activity	[α]20/D −69°, c = 0.5 in ethanol
Application	Useful chiral ligand for catalytic asymmetric aldol reactions. Mukaiyama, T.1

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation

Precautionary statements

P305IF IN EYES

Protective equipment	Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point	105 °C / 221 °F
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/38
Safety statements (S)	26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

84466-85-3

MDL number

MFCD18642280

Beilstein registry

4242955

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-1-[(1-Methyl-2-pyrrolidinyl)methyl]piperidine used for?

This compound is primarily used as a chiral ligand in catalytic asymmetric synthesis, notably in asymmetric aldol reactions. It also serves as a versatile heterocyclic building block for constructing complex organic molecules.

What is the CAS number and molecular formula?

The CAS number is 84466-85-3, and the molecular formula is C11H22N2.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical with a minimum assay of 97%. TSS does not represent this product as USP, BP, or EP grade; it is intended for research and chemical synthesis purposes.

What are the safety and handling considerations?

This compound is classified with GHS07 and carries a Warning signal word. It is associated with hazard statements H315 (Causes skin irritation) and H319 (Causes serious eye irritation). Appropriate personal protective equipment, including eyeshields and gloves, should be used. Consult the Safety Data Sheet for detailed handling and emergency procedures.

Is this compound a controlled substance?

The provided data does not indicate that (S)-1-[(1-Methyl-2-pyrrolidinyl)methyl]piperidine is a controlled substance.

How are products packed and shipped?

Tech Serve Solutions securely packs and exports chemicals globally, adhering to all relevant transport regulations to ensure safe delivery.

How can I request a quote or sample?

To request a quote or sample, please contact our sales department via the website or direct email, providing the product name and CAS number (84466-85-3).