(S)-1-Z-4-oxopyrrolidine-2-carboxylic acid

CAS 64187-47-9C13H13NO5Chemical Synthesis

(S)-1-Z-4-oxopyrrolidine-2-carboxylic acid (CAS 64187-47-9, C13H13NO5) is a high-purity chiral building block with a molecular weight of 263.25. This derivative of proline is valuable in asymmetric synthesis and peptide chemistry. It serves as a key intermediate in the construction of complex heterocyclic structures and unnatural amino acid derivatives, offering precise stereochemical control for advanced chemical research and development applications.

IUPAC: 1-Cbz-4-oxo-L-proline,Z-4-oxo-L-proline

Email us

(S)-1-Z-4-oxopyrrolidine-2-carboxylic acid (C13H13NO5) — chemical structure, CAS 64187-47-9; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisChemical BiologyChemical SynthesisChiral Building BlocksHeterocyclic Building BlocksPeptide ChemistryProline DerivativesPyrrolidines

01 /Applications

Asymmetric Synthesis

Utilised as a chiral synthon for the enantioselective preparation of complex organic molecules. Its defined stereochemistry enables the controlled introduction of chirality in target compounds.

Peptide Chemistry

Incorporated into peptide sequences as an unnatural amino acid derivative to modify peptide structure and function. It is valuable for creating novel peptidomimetics and modified peptides.

Heterocyclic Chemistry

Serves as a versatile building block for synthesizing substituted pyrrolidine rings and other heterocyclic frameworks. These structures are prevalent in pharmaceuticals and biologically active molecules.

Chemical Biology Research

Employed in the design and synthesis of probes and specialised molecules for studying biological systems. Its unique structural features can be exploited for molecular recognition and targeting.

02 /Properties

Molecular weight	263.25
Empirical formula	C13H13NO5
Assay	97%
Optical activity	[α]22/D +6.0°, c = 1 in chloroform
Melting point	98-102 °C

03 /Safety & handling

GHS hazard pictogram: Harmful / irritant (GHS07) — Harmful / irritant

Warning

Hazard statements

H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust, fume, gas or vapours
P305IF IN EYES

Protective equipment	dust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)	3
Hazard codes (EU)	Xi
Risk statements (R)	36/37/38
Safety statements (S)	26-36-37

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

64187-47-9

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-1-Z-4-oxopyrrolidine-2-carboxylic acid used for?

(S)-1-Z-4-oxopyrrolidine-2-carboxylic acid is primarily used in asymmetric synthesis, peptide chemistry, and the construction of heterocyclic compounds, particularly as a chiral building block for unnatural amino acid derivatives and research into chemical biology.

What are the CAS number and formula for this compound?

The CAS number is 64187-47-9, and the empirical formula is C13H13NO5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies (S)-1-Z-4-oxopyrrolidine-2-carboxylic acid with an assay of 97%. This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeial grade.

What are the primary safety hazards associated with this chemical?

This compound is a warning-level chemical that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Appropriate PPE, including a dust mask (type N95 US), eyeshields, and gloves, is essential during handling. Ensure adequate ventilation and avoid breathing dust.

Is this chemical shipped internationally?

Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, and (S)-1-Z-4-oxopyrrolidine-2-carboxylic acid can be packed and exported worldwide.

How can I request a quote or sample?

To request a quote or a sample, please contact our sales department through the website or by phone. Provide the product name or CAS number (64187-47-9) for prompt service.