(S)-1-[(R)-α-Methylbenzyl]aziridine-2-methanol
(S)-1-[(R)-α-Methylbenzyl]aziridine-2-methanol (CAS: 173143-73-2, C11H15NO) is a chiral building block with a molecular weight of 177.24 g/mol. This enantiomerically pure compound, featuring both aziridine and chiral alcohol functionalities, is valuable in asymmetric synthesis. It serves as a versatile intermediate for constructing complex chiral molecules in organic chemistry, contributing to the development of new pharmaceuticals and fine chemicals.
- IUPAC
- (S)-1-[(R)-α-Methylbenzyl]-2-aziridinemethanol,[1-(1′(R)-α-methylbenzyl)-aziridine-2(S)-yl]-methanol
- Synonyms
- (S)-1-[(R)-α-Methylbenzyl]-2-aziridinemethanol[1-(1′(R)-α-methylbenzyl)-aziridine-2(S)-yl]-methanol
![(S)-1-[(R)-α-Methylbenzyl]aziridine-2-methanol (C11H15NO) — chemical structure, CAS 173143-73-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F173143-73-2.png&w=3840&q=75)
Chiral Building Block
Utilised as a key stereodefined intermediate in the synthesis of complex chiral molecules. Its distinct stereochemistry makes it invaluable for constructing target compounds with specific enantiomeric requirements.
Asymmetric Synthesis
Serves as a substrate or reagent in asymmetric synthesis methodologies. The presence of defined chiral centres allows for the introduction of stereospecificity in subsequent chemical transformations.
Pharmaceutical Intermediate
Employed in the multi-step synthesis of active pharmaceutical ingredients (APIs). Its structural features can be incorporated into drug candidates, aiding in the development of novel therapeutics.
Organic Synthesis
A versatile reagent for various organic reactions, including ring-opening of the aziridine moiety and functionalisation of the alcohol group. It enables the creation of diverse molecular architectures.
| Molecular weight | 177.24 |
|---|---|
| Empirical formula | C11H15NO |
| Assay | 98% |
| Optical activity | [α]20/D +61°, c = 10% in methylene chloride |
| Optical purity | ee: 98% (GLC) |
| Melting point | 30-35 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-[(R)-α-Methylbenzyl]aziridine-2-methanol used for?
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(S)-1-[(R)-α-Methylbenzyl]aziridine-2-methanol is primarily used as a chiral building block in asymmetric synthesis and as an intermediate in organic and pharmaceutical synthesis.
What is the CAS number and formula for this chemical?
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The CAS number is 173143-73-2 and the empirical formula is C11H15NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at an assay of 98% with an optical purity of ee: 98%. It is not represented as USP/BP/EP grade.
How should (S)-1-[(R)-α-Methylbenzyl]aziridine-2-methanol be handled safely?
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This compound is a Warning substance and may cause skin, eye, and respiratory irritation (H315-H319-H335). Handle with a dust mask type N95 (US), eyeshields, and gloves. Avoid breathing dust/fume/gas/mist/vapours/spray and ensure good ventilation. In case of contact with eyes, rinse cautiously with water for several minutes, removing contact lenses if present and easy to do. Continue rinsing.
How is this product packed, shipped, and exported?
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Tech Serve Solutions ensures appropriate packaging for safe transport and exports chemicals globally, adhering to all relevant regulations.
How can I request a sample or quote for this chemical?
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Please contact our sales team via the website or by phone to request a sample or a quote for (S)-1-[(R)-α-Methylbenzyl]aziridine-2-methanol.
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