(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi(3,5-xylyl)phosphine
(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi(3,5-xylyl)phosphine (CAS 223121-07-1) is a ferrocenylphosphine ligand with the molecular formula C40H40FeP2 and a molecular weight of 638.54 g/mol. This chiral phosphine ligand is a valuable tool in asymmetric synthesis, particularly for catalysis. It is widely recognised as a 'privileged ligand', finding application in various enantioselective transformations within chemical synthesis and pharmaceutical intermediate production.
- IUPAC
- (2S)-1-[(1S)-1-[Bis(3,5-dimethylphenyl)phosphino]ethyl]-2-(diphenylphosphino)ferrocene (acc to CAS),Josiphos SL-J005-2
- Synonyms
- (2S)-1-[(1S)-1-[Bis(3,5-dimethylphenyl)phosphino]ethyl]-2-(diphenylphosphino)ferroceneJosiphos SL-J005-2
![(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi(3,5-xylyl)phosphine (C40H40FeP2) — chemical structure, CAS 223121-07-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F223121-07-1.png&w=3840&q=75)
Asymmetric Catalysis
This ligand is extensively employed as a chiral auxiliary in transition metal-catalysed asymmetric reactions. Its unique structure facilitates high enantioselectivity in transformations such as hydrogenation, hydroformylation, and C-C bond formation.
Pharmaceutical Intermediate Synthesis
The ability to control stereochemistry makes this compound crucial for the synthesis of chiral building blocks and active pharmaceutical ingredients (APIs). It enables the efficient production of enantiomerically pure drug precursors.
Fine Chemical Production
In the broader field of fine chemical manufacturing, this ligand is utilised to achieve stereospecific synthesis of complex organic molecules, where precise control over chirality is paramount.
Ligand Development
As a well-established Josiphos-type ligand, it serves as a benchmark and a starting point for the development of new, highly active chiral ligands for specialised catalytic applications.
| Molecular weight | 638.54 |
|---|---|
| Empirical formula | C40H40FeP2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldi(3,5-xylyl)phosphine used for?
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This compound is primarily used as a chiral ligand in asymmetric catalysis for various chemical synthesis applications, including the production of pharmaceutical intermediates.
What is the CAS number and formula for this product?
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The CAS number is 223121-07-1 and the molecular formula is C40H40FeP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97% and an optical purity of ee: ≥99%. We do not represent this product as USP/BP/EP grade.
What are the safety and handling precautions for this chemical?
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When handling this chemical, it is essential to wear eyeshields and gloves, and use a type N95 (US) or type P1 (EN143) respirator filter. The WGK is 3 (Germany), indicating a high hazard to water.
How is this chemical packed and shipped?
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Tech Serve Solutions securely packs and exports fine chemicals globally, adhering to all relevant shipping and customs regulations.
How can I request a quote or sample?
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To request a quote or sample, please use the contact form on our website or email our sales department directly.
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