(S)-1-[(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine
(S)-1-[(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine (CAS 849924-40-9) is a sophisticated organophosphorus compound with a molecular weight of 658.61 g/mol. As a chiral ligand, it is primarily utilized in asymmetric synthesis to facilitate the enantioselective production of chiral molecules. Its unique structural features enable high catalytic activity and selectivity in various organic transformations, making it a valuable tool in pharmaceutical and fine chemical research and development.
- IUPAC
- (2S)-1-[(1S)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-[bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocene (acc to CAS),Josiphos SL-J013-2
- Synonyms
- C38H52FeO2P2Josiphos SL-J013-2
![(S)-1-[(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine (C38H52FeO2P2) — chemical structure, CAS 849924-40-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F849924-40-9.png&w=3840&q=75)
Asymmetric Catalysis
This ferrocenyl phosphine ligand is instrumental in asymmetric catalysis, promoting enantioselective reactions such as hydrogenation, cross-coupling, and isomerisation. It enables precise control over stereochemistry, crucial for synthesizing enantiomerically pure active pharmaceutical ingredients (APIs).
Chiral Ligand Development
As a member of the Josiphos family, this compound serves as a privileged ligand in the development of new catalytic systems. Its modular structure allows for fine-tuning of electronic and steric properties to optimize performance in specific chemical syntheses.
Pharmaceutical Intermediate Synthesis
The ligand's ability to induce high enantioselectivity makes it highly relevant for the synthesis of complex chiral intermediates required in the pharmaceutical industry. This aids in the efficient and stereospecific production of drug candidates.
Fine Chemical Production
Beyond pharmaceuticals, this catalyst ligand finds application in the broader fine chemical sector for producing stereochemically defined molecules used in agrochemicals, materials science, and flavour and fragrance industries.
| Molecular weight | 658.61 |
|---|---|
| Empirical formula | C38H52FeO2P2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-[(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine used for?
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(S)-1-[(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine is primarily used as a chiral ligand in asymmetric catalysis for the enantioselective synthesis of chiral molecules, particularly in the pharmaceutical and fine chemical industries.
What are the CAS number and molecular formula for this compound?
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The CAS number is 849924-40-9, and the empirical formula is C38H52FeO2P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound with an assay of ≥97% and an optical purity (ee) of ≥99%. We do not represent this product as USP, BP, EP, or for nutraceutical or food use.
How should this chemical be handled safely?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound is classified with WGK Germany 3, indicating a significant hazard to water.
Is this chemical controlled or scheduled?
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The provided data does not indicate that this chemical is controlled or scheduled.
How can I request a sample or quote for this chemical?
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To request a sample or a quote, please contact our sales team through the TSS website, providing the product name and CAS number (849924-40-9).
Is this product exported by TSS?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including this product.
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