(S)-1-{(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethyldi(3,5-xylyl)phosphine
(S)-1-{(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethyldi(3,5-xylyl)phosphine (CAS 849924-48-7) is a sophisticated chiral phosphine ligand with a molecular weight of 754.70 g/mol. As a key component in asymmetric synthesis, it is instrumental in catalysing the formation of enantiomerically pure compounds. This advanced ligand is primarily employed in sophisticated chemical synthesis processes requiring high stereoselectivity, making it valuable for pharmaceutical and fine chemical research and development.
- IUPAC
- (2S)-1-[(1S)-1-[Bis(3,5-dimethylphenyl)phosphino]ethyl]-2-[bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocene (acc to CAS),Josiphos SL-J418-2
- Synonyms
- 849924-48-7C46H52FeO2P2Josiphos SL-J418-2
![(S)-1-{(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethyldi(3,5-xylyl)phosphine (C46H52FeO2P2) — chemical structure, CAS 849924-48-7; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F849924-48-7.png&w=3840&q=75)
Asymmetric Catalysis
This Josiphos-type ligand is extensively utilised as a chiral auxiliary in transition metal-catalysed asymmetric reactions. It facilitates the enantioselective synthesis of valuable chiral molecules, which are crucial intermediates in the pharmaceutical industry.
Homogeneous Catalysis
It serves as a highly effective ligand in various homogeneous catalytic transformations. Its unique electronic and steric properties allow for fine-tuning of catalyst activity and selectivity in complex organic synthesis.
Pharmaceutical Intermediate Synthesis
The compound's ability to induce high enantioselectivity makes it an indispensable tool for the synthesis of chiral active pharmaceutical ingredients (APIs) and their precursors. It enables the production of single-enantiomer drugs with improved efficacy and safety profiles.
| Molecular weight | 754.70 |
|---|---|
| Empirical formula | C46H52FeO2P2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-{(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethyldi(3,5-xylyl)phosphine used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis and homogeneous catalysis, particularly for the enantioselective production of valuable chiral molecules and pharmaceutical intermediates.
What are the CAS number and formula for this chemical?
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The CAS number is 849924-48-7 and the empirical formula is C46H52FeO2P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of ≥97% and optical purity (ee) of ≥99%. We do not represent this product as USP, BP, or EP grade.
How is this chemical handled and what are the safety precautions?
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The product is classified with WGK 3 (Germany). Recommended personal protective equipment includes eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is advised for respiratory protection. Handle with care to avoid exposure.
How is this product packed, shipped, and exported?
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Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, ensuring products are appropriately packed for safe transit and compliant with international shipping regulations.
How can I request a sample or quote for this chemical?
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Please contact our sales team directly through our website or by phone to request a sample or obtain a quotation for (S)-1-{(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethyldi(3,5-xylyl)phosphine.
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