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(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine

CAS 162291-02-3C36H44FeP2 · C2H5OHChemical Synthesis

(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine (CAS 162291-02-3), an ethanol adduct with the formula C36H44FeP2 · C2H5OH and a molecular weight of 640.60, is a key chiral ligand. It is widely utilised in asymmetric synthesis for creating enantiomerically enriched products, particularly in catalytic applications where precise stereochemical control is essential. Its unique structure makes it valuable in various cross-coupling reactions.

IUPAC
(2S)-1-[(1S)-1-(Dicyclohexylphosphino)ethyl]-2-(diphenylphosphino)ferrocene (acc to CAS),(S)-(R)-Josiphos,Josiphos SL-J001-2
Synonyms
(2S)-1-[(1S)-1-(Dicyclohexylphosphino)ethyl]-2-(diphenylphosphino)ferrocene (acc to CAS)(S)-(R)-JosiphosJosiphos SL-J001-2
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(S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine (C36H44FeP2 · C2H5OH) — chemical structure, CAS 162291-02-3; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral CatalystsLigandsand ReagentsJosiphos Ligands
01 /Applications

Asymmetric Catalysis

This chiral ferrocenyl phosphine ligand is instrumental in asymmetric catalysis, enabling the selective synthesis of chiral molecules. It is particularly effective in transition metal-catalyzed reactions, facilitating high enantioselectivity.

Homogeneous Catalysis

Utilised as a ligand in homogeneous catalysis, it forms active catalytic species with transition metals. These complexes are employed in a variety of organic transformations requiring stereochemical control.

Pharmaceutical Intermediate Synthesis

Its ability to control stereochemistry makes it a valuable tool for the synthesis of complex pharmaceutical intermediates where specific enantiomers are required for biological activity.

Fine Chemical Production

This ligand finds application in the production of fine chemicals, where enantiomeric purity is often a critical specification for the final product's performance and properties.

02 /Properties
Molecular weight640.60
Empirical formulaC36H44FeP2 · C2H5OH
Assay≥97%
Optical purityee: ≥99%
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
162291-02-3
MDL number
MFCD00800285
05 /Additional specifications
Descriptionethanol adduct
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine used for?

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This compound is primarily used as a chiral ligand in asymmetric synthesis and homogeneous catalysis to produce enantiomerically enriched compounds, including pharmaceutical intermediates and fine chemicals.

What are the CAS number and formula for this product?

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The CAS number is 162291-02-3, and the formula is C36H44FeP2 · C2H5OH.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this product with an assay of ≥97% and an optical purity of ee: ≥99%. We do not represent this product as USP, BP, or EP grade.

What are the safety considerations when handling this chemical?

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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound is classified with WGK Germany 3.

How is this chemical packed and shipped?

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Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging for safe transport according to international regulations.

How can I request a sample or quote?

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Please contact our sales team via the website or by phone to request a sample or a detailed quote for (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine.

Need (S)-1-[(RP)-2-(Diphenylphosphino)ferrocenyl]ethyldicyclohexylphosphine in a specific grade or volume?