(S)-1-{(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethylbis(2-methylphenyl)phosphine
(S)-1-{(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethylbis(2-methylphenyl)phosphine (CAS 849924-52-3) is a sophisticated organophosphorus compound with the formula C44H48FeO2P2 and a molecular weight of 726.64 g/mol. This chiral ferrocenyl phosphine ligand is primarily utilised in asymmetric catalysis for the synthesis of enantiomerically pure compounds, playing a crucial role in modern organic synthesis and pharmaceutical development.
- IUPAC
- (1S)-1-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]-2-[(1S)-1-[bis(2-methylphenyl)phosphino]ethyl]ferrocene (acc to CAS),Josiphos SL-J425-2
- Synonyms
- C44H48FeO2P2849924-52-3
![(S)-1-{(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethylbis(2-methylphenyl)phosphine (C44H48FeO2P2) — chemical structure, CAS 849924-52-3; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F849924-52-3.png&w=3840&q=75)
Asymmetric Catalysis
This ferrocenyl-based phosphine ligand is a key component in homogeneous asymmetric catalysis, enabling the stereoselective synthesis of chiral molecules. It is particularly effective in various transition metal-catalyzed reactions, such as hydrogenation and C-C bond formation.
Chiral Ligand Design
The unique structure of this compound, featuring a ferrocene backbone and bulky phosphine groups, makes it a valuable building block for designing highly efficient chiral catalysts. Its application is critical in achieving high enantioselectivity in complex synthetic routes.
Pharmaceutical Intermediate Synthesis
In the pharmaceutical industry, this ligand is instrumental in the asymmetric synthesis of drug intermediates, ensuring the production of enantiomerically pure active pharmaceutical ingredients (APIs). This is vital for drug efficacy and safety.
| Molecular weight | 726.64 |
|---|---|
| Empirical formula | C44H48FeO2P2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-{(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethylbis(2-methylphenyl)phosphine used for?
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(S)-1-{(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethylbis(2-methylphenyl)phosphine is primarily used as a chiral ligand in asymmetric catalysis for the stereoselective synthesis of enantiomerically pure compounds, particularly in the pharmaceutical and fine chemical industries.
What is the CAS number and formula for this chemical?
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The CAS number is 849924-52-3, and the empirical formula is C44H48FeO2P2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97% and an optical purity of ee: ≥99%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling this compound?
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Handle this compound with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if airborne exposure is possible. The compound is classified with WGK Germany 3, indicating a high hazard level.
How is this chemical packed and shipped by Tech Serve Solutions?
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Tech Serve Solutions, a global supplier and exporter, ensures appropriate packaging and shipping for this chemical in compliance with international regulations for hazardous materials.
How can I request a sample or quote for this product?
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To request a sample or a quote for (S)-1-{(RP)-2-[Bis(4-methoxy-3,5-dimethylphenyl)phosphino]ferrocenyl}-ethylbis(2-methylphenyl)phosphine, please visit the Tech Serve Solutions website or contact our sales team directly.
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