4-Methyl-3-nitroanisole
4-Methyl-3-nitroanisole (CAS: 17484-36-5), with the molecular formula CH3C6H3(NO2)OCH3 and a molecular weight of 167.16 g/mol, is a nitro compound utilised as a building block in organic synthesis. It serves as a precursor for the development of various chemical entities. Its primary applications lie in research and development, particularly in the synthesis of more complex molecules, including potential pharmaceutical intermediates.
- IUPAC
- 4-Methoxy-2-nitrotoluene
Synthesis of Antibody Catalysts
4-Methyl-3-nitroanisole has been employed as an external standard in the synthesis of antibody catalysts using a bait-and-switch hapten strategy. This application highlights its role in specialised biochemical research.
Precursor for Enzyme Inhibitors
This compound serves as a starting material for the synthesis of novel 4-fluoro and 2-fluoro-substituted acetylcholinesterase inhibitors. These derivatives are of interest in medicinal chemistry research.
Organic Synthesis Building Block
As a versatile nitro compound, 4-Methyl-3-nitroanisole is valuable in general organic synthesis. It can be incorporated into various reaction pathways to create diverse molecular structures.
| Molecular weight | 167.16 |
|---|---|
| Linear formula | CH3C6H3(NO2)OCH3 |
| Assay | 99% |
| Boiling point | 266-267 °C(lit.) |
| Density | 1.207 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.552(lit.) |
| Application | 4-Methyl-3-nitroanisole was used as external standard in synthesis of antibody catalysts by bait and switch hapten strategy1. It was used as starting material for synthesis of 4-fluoro and 2-fluoro-substituted acetylcholinesterase inhibitors2. |
| Melting point | 17 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 110 °C / 230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methyl-3-nitroanisole used for?
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4-Methyl-3-nitroanisole is primarily used as a building block in organic synthesis, including the preparation of antibody catalysts and as a precursor for enzyme inhibitors. It is also utilised as an external standard in research settings.
What is the CAS number and formula for 4-Methyl-3-nitroanisole?
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The CAS number for 4-Methyl-3-nitroanisole is 17484-36-5, and its chemical formula is CH3C6H3(NO2)OCH3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methyl-3-nitroanisole with a minimum assay of 99%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or other pharmacopoeia grades.
How should 4-Methyl-3-nitroanisole be handled safely?
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4-Methyl-3-nitroanisole is classified as harmful if swallowed and causes serious eye irritation. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection, should be used. Handle in a well-ventilated area and avoid ingestion and eye contact.
Is 4-Methyl-3-nitroanisole a controlled substance?
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The provided data does not indicate that 4-Methyl-3-nitroanisole is a controlled substance. However, users should always comply with local regulations.
How can I request a quote or sample for 4-Methyl-3-nitroanisole?
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To request a quote or sample of 4-Methyl-3-nitroanisole, please contact the Tech Serve Solutions sales team through our website or by phone, providing your specific requirements.
Is 4-Methyl-3-nitroanisole available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 4-Methyl-3-nitroanisole, and can facilitate international shipments.
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