4-Methyl-3-nitrobenzenesulfonyl chloride
4-Methyl-3-nitrobenzenesulfonyl chloride (CAS: 616-83-1), with the molecular formula C7H6ClNO4S and a molecular weight of 235.64 g/mol, is a key organic building block. This sulfonyl halide is recognised for its reactivity in chemical synthesis, serving as an intermediate in the preparation of more complex organic molecules within research and industrial settings. Its specific structure makes it valuable for introducing the 4-methyl-3-nitrobenzenesulfonyl group into various chemical structures.

Organic Synthesis Intermediate
Utilised as a versatile building block in organic chemistry for the synthesis of diverse target molecules. It is particularly useful for introducing the 4-methyl-3-nitrobenzenesulfonyl moiety into compounds.
Pharmaceutical Research
Serves as a precursor or intermediate in the multi-step synthesis of potential pharmaceutical agents. Its reactivity allows for its incorporation into complex molecular frameworks under investigation.
Specialty Chemical Manufacturing
Employed in the production of specialised chemicals where the specific sulfonyl chloride functionality is required. This can include dyes, agrochemicals, or other fine chemical applications.
| Molecular weight | 235.64 |
|---|---|
| Empirical formula | C7H6ClNO4S |
| Assay | 97% |
| Melting point | 30-34 °C(lit.) |

Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Flash point | >110 °C / >230 °F |
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Methyl-3-nitrobenzenesulfonyl chloride used for?
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4-Methyl-3-nitrobenzenesulfonyl chloride (CAS: 616-83-1) is primarily used as a building block and intermediate in organic synthesis, including pharmaceutical research and specialty chemical manufacturing. It is valuable for introducing the 4-methyl-3-nitrobenzenesulfonyl group into various chemical structures.
What is the CAS number and molecular formula for 4-Methyl-3-nitrobenzenesulfonyl chloride?
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The CAS number for 4-Methyl-3-nitrobenzenesulfonyl chloride is 616-83-1. Its empirical formula (Hill notation) is C7H6ClNO4S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Methyl-3-nitrobenzenesulfonyl chloride with a minimum assay of 97%. This product is typically supplied as a technical or research grade material, and TSS does not represent it as USP, BP, EP, or other pharmacopoeia grades unless explicitly stated.
How should 4-Methyl-3-nitrobenzenesulfonyl chloride be handled safely?
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4-Methyl-3-nitrobenzenesulfonyl chloride is classified as Danger (GHS05) and causes severe skin burns and eye damage (H314). Appropriate personal protective equipment, including eyeshields, face shields, gloves, and suitable respiratory protection (e.g., N100 respirator), must be used. Handle in a well-ventilated area. Refer to the Safety Data Sheet (SDS) for comprehensive handling instructions.
Is this chemical suitable for export?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including 4-Methyl-3-nitrobenzenesulfonyl chloride. We adhere to all international shipping regulations for chemicals, including UN 3261, Class 8, Packing Group III.
How can I request a sample or a quote for 4-Methyl-3-nitrobenzenesulfonyl chloride?
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To request a sample or obtain a quote for 4-Methyl-3-nitrobenzenesulfonyl chloride, please visit the Tech Serve Solutions website or contact our sales department directly. Specify the quantity and your delivery location for a prompt response.
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