(S)-1-{(RP)-2-[Bis[4-(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi-tert-butylphosphine
(S)-1-{(RP)-2-[Bis[4-(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi-tert-butylphosphine (CAS: 849924-37-4) is a chiral organophosphorus compound with the formula C34H38F6FeP2 and a molecular weight of 678.45 g/mol. This specialised ligand is primarily employed in asymmetric catalysis to facilitate enantioselective transformations. Its unique structural features enable high levels of stereocontrol in various synthetic applications, making it a valuable tool for chemists seeking to synthesise chiral molecules.
- IUPAC
- (2S)-1-[(1S)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-[bis[4-(trifluoromethyl)phenyl]phosphino]ferrocene (acc to CAS),Josiphos SL-J011-2
![(S)-1-{(RP)-2-[Bis[4-(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi-tert-butylphosphine (C34H38F6FeP2) — chemical structure, CAS 849924-37-4; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F849924-37-4.png&w=3840&q=75)
Asymmetric Hydrogenation
This Josiphos-type ligand is highly effective in catalysing asymmetric hydrogenation reactions, enabling the stereoselective reduction of prochiral substrates. It is particularly useful for the synthesis of chiral amines and alcohols.
Cross-Coupling Reactions
The compound serves as a privileged ligand in palladium-catalysed cross-coupling reactions. Its specific electronic and steric properties can influence reaction rates and selectivity, contributing to the formation of complex organic molecules.
Chiral Catalyst Development
As a highly enantiopure ligand, it is instrumental in the development and application of chiral catalysts for fine chemical synthesis. Researchers utilise its properties to achieve precise stereochemical outcomes in challenging transformations.
| Molecular weight | 678.45 |
|---|---|
| Empirical formula | C34H38F6FeP2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-{(RP)-2-[Bis[4-(trifluoromethyl)phenyl]phosphino]ferrocenyl}ethyldi-tert-butylphosphine used for?
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This compound is used as a chiral ligand in asymmetric catalysis, particularly for enantioselective transformations such as hydrogenation and cross-coupling reactions, aiding in the synthesis of chiral molecules.
What are the CAS number and formula for this chemical?
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The CAS number is 849924-37-4 and the molecular formula is C34H38F6FeP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97% and an optical purity (ee) of ≥99%. This is a research grade material and is not represented as USP, BP, or EP.
What are the safety and handling considerations for this compound?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified with WGK Germany 3, indicating it is a hazard to water.
Does Tech Serve Solutions export this chemical?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, and can ship this product internationally.
How can I request a quote or sample?
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Please contact our sales team via the website to request a quote or a sample of this chemical.
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