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(S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethylbis(2-methylphenyl)phosphine

CAS 849924-74-9C34H32FeO2P2Chemical Synthesis

(2S)-1-{(1S)-1-[Bis(2-methylphenyl)phosphino]ethyl}-2-(di-2-furanylphosphino)ferrocene, CAS 849924-74-9, has the molecular formula C34H32FeO2P2 and a molecular weight of 590.41 g/mol. This chiral ferrocenyl phosphine ligand, also known as a Josiphos ligand, is a highly effective catalyst component for asymmetric synthesis. It is widely utilised in the preparation of enantiomerically pure compounds for pharmaceutical and fine chemical industries, offering excellent stereochemical control.

IUPAC
(2S)-1-[(1S)-1-[Bis(2-methylphenyl)phosphino]ethyl]-2-(di-2-furanylphosphino)ferrocene (acc to CAS),Josiphos SL-J452-2
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(S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethylbis(2-methylphenyl)phosphine (C34H32FeO2P2) — chemical structure, CAS 849924-74-9; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral CatalystsLigandsand ReagentsJosiphos Ligands
01 /Applications

Asymmetric Catalysis

Serves as a key chiral ligand in transition metal-catalyzed asymmetric reactions, facilitating the synthesis of enantiomerically enriched molecules. Its unique structure promotes high stereoselectivity and enantioselectivity in various transformations.

Pharmaceutical Intermediates Synthesis

Crucial for the stereoselective synthesis of complex chiral building blocks and intermediates used in the development of active pharmaceutical ingredients (APIs). Enables efficient routes to optically pure drug candidates.

Fine Chemical Production

Employed in the production of high-value fine chemicals where precise stereochemical control is paramount. Applications include the synthesis of agrochemicals, fragrances, and advanced materials.

Research and Development

An indispensable tool in academic and industrial research laboratories exploring new catalytic methodologies and developing novel asymmetric synthetic strategies. Supports innovation in chiral chemistry.

02 /Properties
Molecular weight590.41
Empirical formulaC34H32FeO2P2
Assay≥97%
Optical purityee: ≥99%
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
849924-74-9
MDL number
MFCD08561169
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (2S)-1-{(1S)-1-[Bis(2-methylphenyl)phosphino]ethyl}-2-(di-2-furanylphosphino)ferrocene used for?

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This compound is primarily used as a chiral phosphine ligand in asymmetric catalysis for the synthesis of enantiomerically pure compounds, particularly in the pharmaceutical and fine chemical industries.

What are the CAS number and formula for this chemical?

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The CAS number is 849924-74-9 and the empirical formula (Hill notation) is C34H32FeO2P2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this product with an assay of ≥97% and an optical purity (ee) of ≥99%. This is a research-grade chemical and is not supplied as USP, BP, EP, or pharmaceutical grade.

What are the safety and handling considerations for this product?

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This compound is classified with a WGK Germany rating of 3, indicating it is hazardous. Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used during handling.

How is this chemical packed and shipped?

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Tech Serve Solutions, as a specialist global supplier and exporter, ensures appropriate packaging and adherence to international shipping regulations for fine chemicals.

How can I request a quote or sample?

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To request a quote or a sample, please contact the Tech Serve Solutions sales team via our website or by phone.

Need (S)-1-{(RP)-2-[Di(2-furyl)phosphino]ferrocenyl}ethylbis(2-methylphenyl)phosphine in a specific grade or volume?