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(S)-1-{(SP)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl}ethylbis[3,5-bis-(trifluoromethyl)phenyl]phosphine

CAS 849925-17-3C46H32F12FeP2Chemical Synthesis

(S)-1-{(SP)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl}ethylbis[3,5-bis-(trifluoromethyl)phenyl]phosphine (CAS 849925-17-3) is a sophisticated organophosphorus compound with a molecular weight of 930.52 g/mol. This chiral ferrocenyl phosphine ligand is primarily employed in asymmetric synthesis and catalysis. Its unique structure facilitates highly enantioselective transformations, making it an invaluable tool in the synthesis of complex chiral molecules for pharmaceutical and fine chemical industries.

IUPAC
(1R)-1-[(1S)-1-[Bis(3,5-bis(trifluoromethyl)phenyl)phosphino]ethyl]-2-[2-(diphenylphosphino)phenyl]ferrocene (acc to CAS),Walphos SL-W001-2
Synonyms
C46H32F12FeP2(1R)-1-[(1S)-1-[Bis(3,5-bis(trifluoromethyl)phenyl)phosphino]ethyl]-2-[2-(diphenylphosphino)phenyl]ferrocene
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(S)-1-{(SP)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl}ethylbis[3,5-bis-(trifluoromethyl)phenyl]phosphine (C46H32F12FeP2) — chemical structure, CAS 849925-17-3; Chemistry, fine chemical supplied by Tech Serve Solutions
Asymmetric SynthesisChemical SynthesisChiral CatalystsLigandsand ReagentsWalphos Ligands More...
01 /Applications

Asymmetric Catalysis

This ligand is extensively used in transition metal-catalysed asymmetric reactions, such as hydrogenation, C-C bond formation, and C-N bond formation. It enables the synthesis of enantiomerically enriched products with high selectivity.

Chiral Ligand Development

As a privileged chiral ligand, it serves as a crucial component in the development of novel catalytic systems. Its distinct steric and electronic properties allow for fine-tuning of catalyst performance in various organic transformations.

Pharmaceutical Intermediate Synthesis

The high enantioselectivity offered by this phosphine ligand makes it ideal for constructing chiral centres found in many active pharmaceutical ingredients (APIs) and their intermediates, ensuring the production of specific stereoisomers.

02 /Properties
Molecular weight930.52
Empirical formulaC46H32F12FeP2
Assay≥97%
Optical purityee: ≥99%
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
849925-17-3
MDL number
MFCD04117710
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (S)-1-{(SP)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl}ethylbis[3,5-bis-(trifluoromethyl)phenyl]phosphine used for?

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This compound is primarily used as a chiral ligand in asymmetric synthesis and catalysis, particularly for creating enantiomerically enriched complex molecules.

What is the CAS number and formula for this compound?

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The CAS number is 849925-17-3, and the empirical formula is C46H32F12FeP2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies this compound with an assay of ≥97% and an optical purity of ee: ≥99%. It is supplied as a research-grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeia standard.

How should this chemical be handled?

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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK Germany 3, indicating it is hazardous to water.

How is this chemical shipped and exported?

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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, pharmaceutical intermediates, and laboratory reagents, adhering to all necessary regulations for international shipment.

How can I request a sample or quote?

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Please contact our sales team or use the product inquiry form on our website to request a sample or a detailed quotation.

Need (S)-1-{(SP)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl}ethylbis[3,5-bis-(trifluoromethyl)phenyl]phosphine in a specific grade or volume?