(S)-1-{(RP)-2-[Di(1-naphthyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine
(S)-1-{(RP)-2-[Di(1-naphthyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine (CAS 849924-44-3) is a chiral ferrocenyl phosphine ligand with the formula C40H44FeP2 and a molecular weight of 642.57 g/mol. This compound is crucial in asymmetric synthesis, serving as a highly effective chiral catalyst and ligand. Its unique structure facilitates enantioselective transformations, making it valuable in the development of complex molecules and pharmaceutical intermediates.
- IUPAC
- (2S)-1-[(1S)-1-[Bis(1,1-dimethylethyl)phosphino]ethyl]-2-(di-1-naphthalenylphosphino)ferrocene (acc to CAS),Josiphos SL-J216-2
![(S)-1-{(RP)-2-[Di(1-naphthyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine (C40H44FeP2) — chemical structure, CAS 849924-44-3; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F849924-44-3.png&w=3840&q=75)
Asymmetric Catalysis
Utilised as a chiral ligand in transition metal-catalyzed reactions to achieve high enantioselectivity. It is particularly effective in asymmetric hydrogenation and other stereoselective bond formations.
Pharmaceutical Intermediate Synthesis
Enables the enantioselective synthesis of chiral building blocks essential for the production of active pharmaceutical ingredients (APIs). Its application aids in developing stereochemically pure drug candidates.
Organometallic Chemistry
Serves as a sophisticated ligand in organometallic complexes, influencing the reactivity and selectivity of metal centres in various catalytic cycles.
Research and Development
Employed in academic and industrial research laboratories for exploring novel synthetic methodologies and developing new chiral technologies.
| Molecular weight | 642.57 |
|---|---|
| Empirical formula | C40H44FeP2 |
| Assay | ≥97% |
| Optical purity | ee: ≥99% |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (S)-1-{(RP)-2-[Di(1-naphthyl)phosphino]ferrocenyl}ethyldi-tert-butylphosphine used for?
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This compound is primarily used as a chiral ligand in asymmetric synthesis, particularly in transition metal catalysis for enantioselective transformations, and for the synthesis of pharmaceutical intermediates.
What are the CAS number and formula for this product?
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The CAS number is 849924-44-3, and the empirical formula is C40H44FeP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of ≥97% and an optical purity of ee: ≥99%. This is a research-grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the safety and handling recommendations?
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This compound requires appropriate personal protective equipment, including eyeshields and gloves. Respiratory protection, such as a type N95 (US) or type P1 (EN143) respirator filter, is recommended. It has a WGK Germany rating of 3, indicating it is hazardous to water.
How is this chemical shipped and exported?
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Tech Serve Solutions, as a global supplier and exporter of fine chemicals, ensures compliant packaging and shipping procedures for international destinations, adhering to all relevant regulations.
How can I request a sample or quote for this product?
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Please contact our sales team via our website or direct email to request a sample or obtain a quotation for this product. We are available to discuss your specific requirements.
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