GF 109203X hydrochloride
GF 109203X hydrochloride (CAS: 176504-36-2) is a potent and selective inhibitor of protein kinase C (PKC) isoforms. Its empirical formula is C25H24N4O2 · HCl, with a molecular weight of 448.94 g/mol. This bioactive small molecule is widely employed in cell biology research to investigate cellular signalling pathways, including autophagy and apoptosis. It serves as a crucial tool for understanding PKC-mediated cellular responses.
- IUPAC
- 3-[1-(Dimethylaminopropyl)indol-3-yl]-4-(indol-3-yl)maleimide hydrochloride,Bisindolylmaleimide I hydrochloride
- Synonyms
- 3-[1-(Dimethylaminopropyl)indol-3-yl]-4-(indol-3-yl)maleimide hydrochloride,Bisindolylmaleimide I hydrochloride
PKC Inhibition for Signalling Pathway Research
GF 109203X hydrochloride selectively inhibits conventional, novel, and atypical protein kinase C isoforms. This makes it invaluable for dissecting the roles of PKC in various cellular processes, including proliferation, differentiation, and survival.
Investigating Autophagy and Apoptosis
As an autophagy activator, this compound is used to study the intricate mechanisms of cellular self-degradation and programmed cell death. Researchers utilise it to modulate autophagic flux and assess its impact on cellular health and disease.
Cellular Neuroscience Studies
The compound's role in cell signaling makes it relevant for neuroscience research, particularly in understanding neuronal function and plasticity. Its application aids in exploring PKC's involvement in neurodegenerative processes and neurological disorders.
| Molecular weight | 448.94 |
|---|---|
| Empirical formula | C25H24N4O2 · HCl |
| Assay | ≥95% |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is GF 109203X hydrochloride used for?
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GF 109203X hydrochloride is used as a selective inhibitor of protein kinase C (PKC) isoforms, acting as an autophagy activator in cell biology research. It is applied to study cell signalling, apoptosis, and neuroscience.
What are the CAS number and formula for GF 109203X hydrochloride?
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The CAS number for GF 109203X hydrochloride is 176504-36-2, and its empirical formula is C25H24N4O2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies GF 109203X hydrochloride with an assay of ≥95%. We do not represent this product as USP, BP, or EP grade; it is suitable for research purposes.
What safety precautions are necessary when handling GF 109203X hydrochloride?
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When handling GF 109203X hydrochloride, it is essential to wear eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound has a WGK Germany classification of 3.
How is GF 109203X hydrochloride stored and shipped?
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GF 109203X hydrochloride should be stored at 2-8°C. Tech Serve Solutions exports this chemical globally, adhering to all relevant shipping regulations for laboratory reagents.
How can I request a quote or sample for GF 109203X hydrochloride?
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To request a quote or sample for GF 109203X hydrochloride, please contact our sales team through our website or by calling our dedicated line.
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