GR 113808
GR 113808 (CAS: 144625-51-4) is a selective serotonin receptor antagonist with the molecular formula C19H27N3O4S and a molecular weight of 393.50 g/mol. This white to light pink solid compound, supplied at ≥98% purity by HPLC, is primarily utilized in biochemical research. Its specific applications include investigations into cell signaling, neuroscience, and the modulation of GPCRs. Storage at 2-8°C is recommended to maintain compound integrity.
- IUPAC
- 1-[2-[(Methylsulfonyl)-amino]ethyl]-4-piperidinyl]methyl 1-methyl-1H-indole-3-carboxylate
Neuroscience Research
GR 113808 serves as a valuable tool in neuroscience research, particularly for studying the role of serotonin receptors in neurotransmission and related cellular processes. Its selective antagonist properties allow for precise investigation of HTR4 receptor function in the central nervous system.
GPCR Modulation Studies
As a GPCR modulator, this compound is employed to understand the complex signaling pathways involving G protein-coupled receptors. Researchers utilise GR 113808 to probe the mechanisms of HTR4 receptor activation and its downstream effects in various biological systems.
Cell Signaling Investigations
The compound is instrumental in elucidating cell signaling cascades. Its ability to block HTR4 receptors provides insights into how these receptors influence intracellular communication and cellular responses in research settings.
Bioactive Small Molecule Research
GR 113808 represents a bioactive small molecule used in drug discovery and development research. Its specific interactions with biological targets make it a candidate for exploring therapeutic strategies, particularly in conditions involving serotonergic pathways.
| Molecular weight | 393.50 |
|---|---|
| Empirical formula | C19H27N3O4S |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to light pink |
| Solubility | DMSO: >20 mg/mL |
| Storage temperature | 2-8°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... HTR4(3360)rat ... Htr3a(79246), Htr4(25324) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is GR 113808 primarily used for?
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GR 113808 is primarily used in research for its selective antagonist activity on serotonin receptors, particularly HTR4, aiding studies in neuroscience, cell signaling, and GPCR modulation.
What are the CAS number and formula for GR 113808?
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The CAS number for GR 113808 is 144625-51-4, and its empirical formula is C19H27N3O4S.
What grade and purity does Tech Serve Solutions supply for GR 113808?
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Tech Serve Solutions supplies GR 113808 at a purity of ≥98% as determined by HPLC. This compound is intended for research use and is not represented as USP, BP, or EP grade.
What are the safety and handling recommendations for GR 113808?
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Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter, should be used when handling GR 113808. Observe GHS hazard information; the compound has a WGK Germany rating of 3.
How is GR 113808 supplied and shipped by TSS?
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GR 113808 is supplied as a solid and should be stored at 2-8°C. Tech Serve Solutions ensures reliable global export of this chemical.
How can I request a sample or a quote for GR 113808?
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To request a sample or a quote for GR 113808, please contact the Tech Serve Solutions sales team through our official website or designated contact channels.
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