Lithium tri-tert-butoxyaluminum hydride
Lithium tri-tert-butoxyaluminum hydride (CAS: 17476-04-9) is a potent reducing agent with the linear formula LiAlH[OC(CH3)3]3. This organometallic compound is known for its high selectivity in organic synthesis, particularly for reductions. It is supplied by Tech Serve Solutions as a 1.0 M solution in THF or as a solid with a typical assay of 97%, making it suitable for advanced chemical research and industrial applications.
- IUPAC
- Lithium aluminum-tri-tert-butoxyhydride
- Synonyms
- Lithium aluminum-tri-tert-butoxyhydride
![Lithium tri-tert-butoxyaluminum hydride (LiAlH[OC(CH3)3]3) — chemical structure, CAS 17476-04-9; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F17476-04-9.png&w=3840&q=75)
Selective Reduction Agent
Lithium tri-tert-butoxyaluminum hydride serves as a highly selective reducing agent in organic synthesis. It is employed to reduce various functional groups under controlled conditions, offering an alternative to more reactive hydrides like lithium aluminum hydride.
Ester and Amide Reduction
This compound is particularly useful for the reduction of esters and amides to primary alcohols and amines, respectively. Its bulky tert-butoxy groups can influence the reactivity and selectivity compared to less sterically hindered aluminum hydrides.
Stereoselective Transformations
In specific synthetic pathways, Lithium tri-tert-butoxyaluminum hydride can be utilized to achieve stereoselective reductions. Its steric profile can be exploited to favour the formation of particular stereoisomers in complex molecule synthesis.
| Molecular weight | 254.27 |
|---|---|
| Linear formula | LiAlH[OC(CH3)3]3 |
| Assay | 97% |
| Density | 0.904 g/mL at 25 °C |
| Concentration | 1.0 M in THF |
| Application | • Reducing agent1 |
| Melting point | 300-319 °C (dec.)(lit.) |
Hazard statements
- H260In contact with water releases flammable gases
- H314Causes severe skin burns and eye damage
Precautionary statements
- P223Do not allow contact with water
- P231Handle under inert gas
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P370In case of fire
- P422
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1409 4.3 / PGI |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 14/15-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Lithium tri-tert-butoxyaluminum hydride used for?
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Lithium tri-tert-butoxyaluminum hydride is primarily used as a selective reducing agent in organic synthesis, particularly for the reduction of esters and amides to alcohols and amines, and in stereoselective transformations.
What is the CAS number and chemical formula for Lithium tri-tert-butoxyaluminum hydride?
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The CAS number for Lithium tri-tert-butoxyaluminum hydride is 17476-04-9. Its linear formula is LiAlH[OC(CH3)3]3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions typically supplies Lithium tri-tert-butoxyaluminum hydride with an assay of 97% as a solid, or as a 1.0 M solution in THF. TSS does not represent this product as USP, BP, or EP grade.
How should Lithium tri-tert-butoxyaluminum hydride be handled safely?
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Lithium tri-tert-butoxyaluminum hydride is a dangerous substance that reacts violently with water (H260) and causes severe skin burns and eye damage (H314). It requires careful handling with appropriate personal protective equipment, including eyeshields, gloves, and a full-face particle respirator, and must be kept away from moisture.
How is Lithium tri-tert-butoxyaluminum hydride packed and shipped?
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Lithium tri-tert-butoxyaluminum hydride is typically packed in UN-approved containers suitable for hazardous materials, adhering to regulations for transport of dangerous goods. We export globally, ensuring compliance with international shipping standards.
How can I request a quote or sample for Lithium tri-tert-butoxyaluminum hydride?
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To request a quote or sample, please contact our sales team through the website or by phone. Provide the product name and CAS number (17476-04-9) for prompt service.
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