GBR 12935 dihydrochloride
GBR 12935 dihydrochloride (CAS 67469-81-2), a potent biogenic amine transport inhibitor, is supplied by Tech Serve Solutions. This compound, with the molecular formula C28H34N2O · 2HCl and a molecular weight of 487.50, is primarily utilised in research settings. It serves as a valuable tool in biochemical studies, particularly within cell biology and neuroscience research, aiding in the investigation of neurotransmitter systems and membrane protein functions.
- IUPAC
- 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride
- Synonyms
- 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine dihydrochloride

Biogenic Amine Transport Inhibition
GBR 12935 dihydrochloride acts as an inhibitor of biogenic amine transport. This property makes it useful for studying the mechanisms of neurotransmitter uptake and clearance in neurological research.
Cellular and Neuroscience Research
This compound is employed as a biochemical reagent in cell biology and neuroscience. It aids in understanding cellular signaling pathways and the function of membrane proteins, particularly in the context of neurotransmission.
Enzyme and Receptor Studies
As a modulator of biogenic amine transport, GBR 12935 dihydrochloride can be used to investigate the activity and regulation of related enzymes and receptors within biological systems.
| Molecular weight | 487.50 |
|---|---|
| Empirical formula | C28H34N2O · 2HCl |
| Assay | ≥98% (TLC) |
| Form | powder |
| Colour | white |
| Solubility | H2O: soluble20 mg/mL (with warming) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is GBR 12935 dihydrochloride used for?
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GBR 12935 dihydrochloride is used in research as a biogenic amine transport inhibitor, particularly in cell biology and neuroscience for studying neurotransmitter systems and membrane protein functions.
What are the CAS number and formula for GBR 12935 dihydrochloride?
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The CAS number for GBR 12935 dihydrochloride is 67469-81-2, and its formula is C28H34N2O · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies GBR 12935 dihydrochloride with an assay of ≥98% (TLC). We do not represent this product as USP, BP, EP or other pharmacopoeia grades.
What are the safety and handling considerations for GBR 12935 dihydrochloride?
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GBR 12935 dihydrochloride requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used. It has a WGK Germany rating of 3, indicating a high hazard to water.
How is GBR 12935 dihydrochloride packed, shipped, and exported?
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GBR 12935 dihydrochloride is carefully packed and exported by Tech Serve Solutions, adhering to all necessary regulations for chemical transport.
How can I request a sample or quote for GBR 12935 dihydrochloride?
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To request a sample or quote for GBR 12935 dihydrochloride, please contact our sales team through the TSS website or direct email.
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