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GR 127935 hydrochloride hydrate

CAS 148642-42-6 (anhydrous)C29H31N5O3 · HCl · xH2OBiochemicals & Reagents

GR 127935 hydrochloride hydrate (CAS: 148642-42-6) is a research chemical supplied by Tech Serve Solutions. With the molecular formula C29H31N5O3 · HCl · xH2O and a molecular weight of 534.05 g/mol (anhydrous basis), this compound is primarily utilised in scientific research, particularly in the fields of cell biology, neuroscience, and pharmacology as a tool for investigating neurotransmission and GPCR activity.

IUPAC
N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2´-methyl-4´-(5-methyl-1,2,4-oxadiazol-3-yl)-1,1´-biphenyl-4-carboxamide hydrochloride hydrate
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GR 127935 hydrochloride hydrate (C29H31N5O3 · HCl · xH2O) — chemical structure, CAS 148642-42-6 (anhydrous); Life Science, fine chemical supplied by Tech Serve Solutions
AntagonistsBioactive Small MoleculesBiochemicals and ReagentsCell BiologyGPCR ModulatorsGPCR ProteinsModulators and AntibodiesGlaxoSmithKlineNeuroscienceNeurotransmission
01 /Applications

Neuroscience Research Tool

GR 127935 hydrochloride hydrate serves as a valuable reagent in neuroscience research for studying neurotransmitter systems and their related receptors, specifically targeting HTR1B and HTR1D.

Pharmacological Research

This compound is employed in pharmacological investigations as an antagonist for G protein-coupled receptors (GPCRs), aiding in the understanding of cellular signaling pathways.

Cell Biology Studies

Utilised in cell biology for exploring membrane protein functions and cellular responses influenced by neurotransmission, offering insights into complex biological mechanisms.

02 /Properties
Molecular weight534.05 (anhydrous basis)
Empirical formulaC29H31N5O3 · HCl · xH2O
Assay>98% (HPLC)
Formpowder
Colourwhite to beige
SolubilityDMSO: soluble10 mg/mL, clear
Storage temperature2-8°C
03 /Safety & handling
Protective equipmentEyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
MDL number
MFCD11045922
05 /Additional specifications
Gene Informationhuman ... HTR1B(3351), HTR1D(3352)
Storage Conditiondesiccated
06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is GR 127935 hydrochloride hydrate used for?

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GR 127935 hydrochloride hydrate is primarily used as a research chemical in neuroscience, pharmacology, and cell biology to study neurotransmission, GPCR activity, and related cellular signaling pathways.

What are the CAS number and formula for GR 127935 hydrochloride hydrate?

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The CAS number for the anhydrous form is 148642-42-6. The empirical formula is C29H31N5O3 · HCl · xH2O.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies GR 127935 hydrochloride hydrate with an assay of >98% purity determined by HPLC. This product is intended for research and laboratory use and is not supplied as USP, BP, or EP grade.

What are the safety and handling considerations for GR 127935 hydrochloride hydrate?

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This compound requires appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection (type N95 or P1 filter). It is classified under WGK Germany 3 and should be handled with care in a well-ventilated area.

How is GR 127935 hydrochloride hydrate shipped and stored?

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GR 127935 hydrochloride hydrate is typically supplied as a white to beige powder. It should be stored at 2-8°C and kept desiccated. TSS exports chemicals globally, adhering to all relevant shipping regulations.

How can I request a sample or quote for GR 127935 hydrochloride hydrate?

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To request a sample or a quote, please contact our sales team through the website or by phone. Provide the product name and CAS number for prompt service.

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