(−)-N-Methylephedrine
(−)-N-Methylephedrine (CAS: 552-79-4; Formula: C11H17NO; Molar Mass: 179.26 g/mol) is a chiral alkaloid derived from Ephedra species. As a purified chemical, it serves as a valuable building block in asymmetric synthesis and chemical research. Its specific stereochemistry makes it useful as a chiral auxiliary. This compound is supplied by TSS for laboratory and industrial applications requiring high chemical purity.
- IUPAC
- (1R,2S)-(−)-2-Dimethylamino-1-phenylpropanol

Chiral Auxiliary in Asymmetric Synthesis
(−)-N-Methylephedrine can be employed as a chiral auxiliary in stereoselective organic reactions. Its well-defined stereochemistry allows for the induction of chirality in newly formed molecules, facilitating the synthesis of enantiomerically pure compounds.
Research Chemical in Cell Biology
This alkaloid finds application in cell biology research, potentially as a tool to study biological pathways or as a reference compound. Its use is confined to experimental settings for scientific investigation.
Intermediate in Chemical Synthesis
As a functionalized organic molecule, (–)-N-Methylephedrine serves as an intermediate in the synthesis of more complex chemical structures. Its amine and hydroxyl functionalities offer versatile reaction sites for various chemical transformations.
| Molecular weight | 179.26 |
|---|---|
| Empirical formula | C11H17NO |
| Assay | ≥98.5% (NT) |
| Grade | puriss. |
| Optical activity | [α]20/D −30±2°, c = 4.5% in methanol |
| Storage temperature | 2-8°C |
| Melting point | 85-88 °C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-N-Methylephedrine used for?
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(–)-N-Methylephedrine is primarily used as a chiral auxiliary in asymmetric synthesis and as a research chemical in cell biology and chemical synthesis.
What are the CAS number and chemical formula for (–)-N-Methylephedrine?
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The CAS number is 552-79-4 and the chemical formula is C11H17NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (–)-N-Methylephedrine with a minimum assay of ≥98.5% (NT), designated as puriss. grade. TSS does not represent this product as USP, BP, or EP grade.
How should (–)-N-Methylephedrine be handled safely?
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Handle with appropriate personal protective equipment including a dust mask (type N95 US), eyeshields, and gloves. Avoid dust formation and ensure adequate ventilation. It is classified as a Warning substance with hazards including skin, eye, and respiratory irritation (H315, H319, H335).
Is (–)-N-Methylephedrine a controlled substance?
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Information regarding controlled substance status is not provided in the product data. Customers are advised to consult local regulations.
How is (–)-N-Methylephedrine packed and exported?
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(–)-N-Methylephedrine is packed according to industry standards for chemical reagents and is available for global export by Tech Serve Solutions.
How can I request a quote or sample?
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Please contact Tech Serve Solutions directly through our website or sales representatives to request a quote or a sample of (–)-N-Methylephedrine.
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