(−)-O,O′-Di-p-toluoyl-L-tartaric acid

CAS 32634-66-5C20H18O8Chemical Synthesis

(−)-O,O′-Di-p-toluoyl-L-tartaric acid (CAS 32634-66-5) is a chiral resolving reagent with the molecular formula C20H18O8 and a molecular weight of 386.35 g/mol. This white to off-white solid is primarily utilised in asymmetric synthesis for the resolution of racemic mixtures. Its specific optical activity and chemical structure make it valuable in the preparation of enantiomerically pure compounds for various chemical and pharmaceutical applications.

Synonyms: C20H18O8(2R,3R)-2,3-bis[(4-methylbenzoyl)oxy]succinic acid(R,R)-(-)-Di-p-toluoyltartaric acid(-)-Di-p-toluoyl-L-tartaric acidDi-p-toluoyl-L-tartaric acid

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(−)-O,O′-Di-p-toluoyl-L-tartaric acid (C20H18O8) — chemical structure, CAS 32634-66-5; Chemistry, fine chemical supplied by Tech Serve Solutions

Asymmetric SynthesisCarboxylic AcidsChemical SynthesisChiral Building BlocksChiral Resolution ReagentsChiral Resolving Reagents

01 /Applications

Chiral Resolution

As a chiral resolving agent, (–)-O,O′-Di-p-toluoyl-L-tartaric acid is employed to separate enantiomers from racemic mixtures. It forms diastereomeric salts with chiral amines or other basic compounds, allowing for their separation by crystallisation.

Asymmetric Synthesis

This compound serves as a crucial building block in asymmetric synthesis. It can be used to induce chirality in chemical reactions or as a chiral auxiliary, leading to the formation of enantiomerically enriched products.

Organic Synthesis

It is a valuable reagent in general organic synthesis, particularly when chirality is a key requirement. Its derivatised tartaric acid structure offers specific stereochemical control in various synthetic strategies.

02 /Properties

Molecular weight	386.35
Empirical formula	C20H18O8
Assay	≥98.0% (T)
Grade	purum
Optical activity	[α]20/D −139±2°, c = 1% in ethanol

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

32634-66-5

MDL number

MFCD00064440

PubChem substance

24867435

Beilstein registry

2022481

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (–)-O,O′-Di-p-toluoyl-L-tartaric acid used for?

(–)-O,O′-Di-p-toluoyl-L-tartaric acid is primarily used as a chiral resolving reagent in asymmetric synthesis to separate enantiomers from racemic mixtures, and as a chiral building block in organic synthesis.

What are the CAS number and formula for this chemical?

The CAS number is 32634-66-5 and the empirical formula is C20H18O8.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this chemical with a grade of 'purum' and an assay of ≥98.0% (T). This product is not represented as USP, BP, or EP grade.

How should (–)-O,O′-Di-p-toluoyl-L-tartaric acid be handled safely?

Handle with appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Ensure good ventilation. The WGK (Germany) rating is 3, indicating it is hazardous to water.

Is this chemical a controlled substance?

The provided data does not indicate that (–)-O,O′-Di-p-toluoyl-L-tartaric acid is a controlled substance.

How is this chemical packed and shipped?

Tech Serve Solutions packs and ships fine chemicals, pharmaceutical intermediates, and laboratory reagents globally, adhering to all necessary regulations for safe transport.