(−)-O,O′-Dibenzoyl-L-tartaric acid mono(dimethylamide)

CAS 78761-37-2C20H19NO7Chemical Synthesis

(−)-O,O′-Dibenzoyl-L-tartaric acid mono(dimethylamide) (CAS 78761-37-2) is a chiral organic compound with the molecular formula C20H19NO7 and a molecular weight of 385.37 g/mol. It serves as a valuable chiral acid, primarily employed in the resolution of amines. Its optical activity, measured at [α]20/D −79±1° (c = 5% in ethanol), underscores its utility in stereoselective applications within chemical synthesis.

Synonyms: C20H19NO7(2R,3R)-2,3-dibenzoyloxy-N,N-dimethylsuccinamic acid

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(−)-O,O′-Dibenzoyl-L-tartaric acid mono(dimethylamide) (C20H19NO7) — chemical structure, CAS 78761-37-2; Chemistry, fine chemical supplied by Tech Serve Solutions

AmidesAsymmetric SynthesisChemical SynthesisChiral Building BlocksChiral Resolution ReagentsChiral Resolving Reagents

01 /Applications

Chiral Resolution of Amines

This compound is specifically designed as a chiral resolving agent. It forms diastereomeric salts with racemic amines, allowing for their separation and the isolation of individual enantiomers.

Asymmetric Synthesis

As a chiral building block and reagent, it plays a role in asymmetric synthesis, contributing to the stereoselective preparation of complex organic molecules where precise stereochemistry is critical.

Preparation of Enantiomerically Pure Compounds

Utilised in the synthesis pathway for enantiomerically pure active pharmaceutical ingredients (APIs) and fine chemicals, where stereoisomeric purity is paramount.

02 /Properties

Molecular weight	385.37
Empirical formula	C20H19NO7
Assay	≥99.0%
Optical activity	[α]20/D −79±1°, c = 5% in ethanol
Application	Chiral acid useful for the resolution of amines
Melting point	150-152 °C (dec.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

78761-37-2

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is (−)-O,O′-Dibenzoyl-L-tartaric acid mono(dimethylamide) used for?

It is primarily used as a chiral resolving agent for the separation of amines and in asymmetric synthesis.

What are the CAS number and molecular formula?

The CAS number is 78761-37-2 and the molecular formula is C20H19NO7.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies this product with an assay of ≥99.0%. It is a technical/research grade material, and TSS does not represent it as USP, BP, or EP grade.

What are the safety and handling considerations?

This compound requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It has a WGK Germany rating of 3, indicating a high hazard to water.