(−)-Norepinephrine
(−)-Norepinephrine (CAS: 51-41-2), a catecholamine with the molecular formula C8H11NO3 and a molecular weight of 169.18 g/mol, is a crucial neurotransmitter and hormone. It plays a vital role in the body's 'fight or flight' response, influencing heart rate, blood pressure, and alertness. Primarily utilised in research settings, it serves as a valuable tool in understanding physiological processes and developing potential therapeutic agents.
- IUPAC
- (R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol,L-Arterenol,L-Noradrenaline,Levarterenol
- Synonyms
- L-ArterenolL-NoradrenalineLevarterenol(R)-4-(2-Amino-1-hydroxyethyl)-1,2-benzenediol
Neuroscience Research
Investigates the role of norepinephrine in neurotransmission, mood regulation, and stress responses within the central and peripheral nervous systems. It is used to study neurological disorders and develop treatments.
Cardiovascular Studies
Employed to understand the physiological effects of norepinephrine on blood pressure, heart rate, and vascular tone. This aids in the research of cardiovascular diseases and their management.
Pharmacological Tool
Serves as a reference compound in drug discovery and development, particularly for agents targeting adrenergic receptors or modulating catecholamine pathways. It aids in screening and testing new drug candidates.
Cellular Signalling Research
Used to explore intracellular signalling cascades initiated by adrenergic receptor activation. This is fundamental to understanding cellular communication and function in various tissues.
| Molecular weight | 169.18 |
|---|---|
| Empirical formula | C8H11NO3 |
| Assay | ≥98.0% (sum of enantiomers, HPLC) |
| Optical activity | [α]20/D −45±3°, c = 5% in 1 M HCl |
| Storage temperature | 2-8°C |
Hazard statements
- H300Fatal if swallowed
- H310Fatal in contact with skin
- H330Fatal if inhaled
Precautionary statements
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P302IF ON SKIN
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 26/27/28 |
| Safety statements (S) | 28-36/37-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-Norepinephrine used for?
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(–)-Norepinephrine is primarily used in research settings, including neuroscience, cardiovascular studies, and as a pharmacological tool to investigate adrenergic pathways and cellular signalling.
What is the CAS number and formula for (–)-Norepinephrine?
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The CAS number for (–)-Norepinephrine is 51-41-2, and its molecular formula is C8H11NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (–)-Norepinephrine with an assay of ≥98.0% (sum of enantiomers, HPLC). This product is intended for research use only and is not represented as USP, BP, EP, or pharmaceutical grade.
How should (–)-Norepinephrine be handled and stored?
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(–)-Norepinephrine is a highly toxic substance and requires stringent safety precautions. Handle with extreme care using appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection (N100 or P3 filters). Store at 2-8°C.
Is (–)-Norepinephrine a controlled substance?
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Based on the provided data, (–)-Norepinephrine is classified with hazard codes T+ (Very Toxic) and has significant hazard statements (H300, H310, H330), indicating high toxicity. It is listed under UN 2811 as a Toxic Solid, Organic, N.O.S. It is essential to consult local regulations regarding its handling and procurement.
How can I request a sample or quote for (–)-Norepinephrine?
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To request a sample or a quotation for (–)-Norepinephrine, please contact the Tech Serve Solutions sales team via our website or your designated account manager.
How is (–)-Norepinephrine packed and shipped?
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(–)-Norepinephrine is packed and shipped according to stringent safety regulations for hazardous materials, including UN 2811 classification. Consult our shipping department for specific details on export and handling.
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