(−)-Nopol
(−)-Nopol (CAS: 35836-73-8, C11H18O, MW: 166.26) is a chiral alcohol with a bicyclic structure. It is primarily employed as a valuable building block in organic synthesis, particularly in asymmetric synthesis due to its inherent chirality. This compound serves as a key intermediate for the creation of more complex molecules, finding utility in research and development settings where precise stereochemical control is paramount for the synthesis of target compounds.
- IUPAC
- (1R)-6,6-Dimethylbicyclo[3.1.1]hept-2-ene-2-ethanol,6,6-Dimethyl-2-norpinene-2-ethanol
- Synonyms
- (1R)-6,6-Dimethylbicyclo[3.1.1]hept-2-ene-2-ethanol,6,6-Dimethyl-2-norpinene-2-ethanol
Chiral Building Block
As a chiral alcohol, (−)-Nopol is utilised as a stereochemically defined starting material for the synthesis of complex organic molecules. Its bicyclic framework offers unique structural features for synthetic manipulation.
Asymmetric Synthesis
The compound's enantiopure nature makes it an ideal precursor in asymmetric synthesis, enabling the stereoselective formation of new chiral centres in target molecules. This is crucial for pharmaceuticals and fine chemicals.
Organic Synthesis Intermediate
(−)-Nopol serves as a versatile intermediate in multi-step organic syntheses. Its reactive alcohol functionality and rigid bicyclic structure allow for diverse chemical transformations to access a range of derivatives.
| Molecular weight | 166.26 |
|---|---|
| Empirical formula | C11H18O |
| Assay | ≥98.0% (sum of enantiomers, GC) |
| Boiling point | 235-236 °C(lit.) |
| Density | 0.967 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.493 |
| Optical activity | [α]20/D −37.0±1°, neat |
Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 98 °C / 208.4 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38 |
| Safety statements (S) | 26-37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (−)-Nopol used for?
+
(−)-Nopol is primarily used as a chiral building block and intermediate in organic synthesis, particularly in asymmetric synthesis, for the construction of complex molecules.
What are the CAS number and formula for (−)-Nopol?
+
The CAS number for (−)-Nopol is 35836-73-8 and its molecular formula is C11H18O.
What grade and purity does Tech Serve Solutions supply for (−)-Nopol?
+
Tech Serve Solutions supplies (−)-Nopol with an assay of ≥98.0% (sum of enantiomers, GC). We do not represent this product as USP, BP, or EP grade.
How should (−)-Nopol be handled safely?
+
(−)-Nopol is classified as harmful if swallowed and causes skin and eye irritation, and may cause respiratory irritation. Appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection, should be used. Handle in a well-ventilated area and avoid contact with skin, eyes, and clothing.
Is (−)-Nopol a controlled substance?
+
Based on the provided data, (−)-Nopol is not indicated as a controlled or scheduled substance.
How is (−)-Nopol packed and shipped?
+
(−)-Nopol is carefully packed according to industry standards to ensure safe transit and is available for global export by Tech Serve Solutions.
How can I request a quote or sample of (−)-Nopol?
+
To request a quote or sample of (−)-Nopol, please contact our sales team through the website or by phone, referencing the product name and CAS number 35836-73-8.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis