(−)-N-Boc-D-α-phenylglycinol
(−)-N-Boc-D-α-phenylglycinol (CAS: 102089-74-7) is a chiral chemical with the linear formula (CH₃)₃CO₂CNHCH(C₆H₅)CH₂OH and a molecular weight of 237.29 g/mol. This compound serves as a valuable chiral synthon in organic synthesis. It is primarily utilised in the preparation of homochiral N-protected β-amino sulfoxides and α-amino acids, as well as a precursor for chiral oxazolidinones.
- IUPAC
- (R)-(−)-2-(Boc-amino)-2-phenylethanol
- Synonyms
- (R)-(−)-2-(Boc-amino)-2-phenylethanol
Chiral Synthon in Organic Synthesis
Utilised for the synthesis of homochiral N-protected β-amino sulfoxides and α-amino acids, leveraging its defined stereochemistry.
Precursor to Chiral Oxazolidinones
Serves as a key intermediate in the preparation of chiral oxazolidinones, which are important structural motifs in pharmaceuticals.
Heterocyclization Reactions
Undergoes heterocyclization reactions, enabling the construction of complex cyclic structures with high stereocontrol.
| Molecular weight | 237.29 |
|---|---|
| Linear formula | (CH3)3CO2CNHCH(C6H5)CH2OH |
| Assay | 99% |
| Optical activity | [α]19/D −38°, c = 1 in chloroform |
| Optical purity | ee: 99% (GLC) |
| Application | Used for the synthesis of homochiral N-protected β-amino sulfoxides1 and α-amino acids.2 Chiral synthon, which undergoes heterocyclizations.3 Precursor to chiral oxazolidinones.4 |
| Melting point | 137-139 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (–)-N-Boc-D-α-phenylglycinol used for?
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(–)-N-Boc-D-α-phenylglycinol is used as a chiral synthon for the synthesis of homochiral N-protected β-amino sulfoxides and α-amino acids. It also serves as a precursor for chiral oxazolidinones and undergoes heterocyclization reactions.
What is the CAS number and formula for (–)-N-Boc-D-α-phenylglycinol?
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The CAS number is 102089-74-7 and the linear formula is (CH₃)₃CO₂CNHCH(C₆H₅)CH₂OH.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (–)-N-Boc-D-α-phenylglycinol with an assay of 99% and optical purity of ee: 99%. We do not represent this product as USP, BP, or EP grade.
How should (–)-N-Boc-D-α-phenylglycinol be handled?
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Handling requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. The compound is classified under WGK 3 in Germany, indicating a high hazard to water.
How is this product packed, shipped, and exported?
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Tech Serve Solutions, a global supplier and exporter, ensures that (–)-N-Boc-D-α-phenylglycinol is packed and shipped according to international safety and regulatory standards.
How can I request a sample or quote for (–)-N-Boc-D-α-phenylglycinol?
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To request a sample or a quotation, please contact our sales department through the website or by phone.
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