(−)-N-Acetylneuraminic acid

CAS 131-48-6C11H19NO9Chemical Synthesis

(−)-N-Acetylneuraminic acid (CAS: 131-48-6, Formula: C11H19NO9, MW: 309.27) is a synthetic crystalline carbohydrate derivative. As a primary component of glycoconjugates like sialoglycoproteins, it plays a vital role in conferring selective binding characteristics. This compound is essential for biochemical studies, metabolism research, and in vitro/in vivo uptake investigations. It also finds application in the development of nanocarrier systems.

IUPAC: Lactaminic acid,NANA,Sialic acid
Synonyms: Lactaminic acidNANASialic acid

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(−)-N-Acetylneuraminic acid (C11H19NO9) — chemical structure, CAS 131-48-6; Chemistry, fine chemical supplied by Tech Serve Solutions

Carbohydrate ChemistryCarbohydrate DerivativesChemical BiologyChemical Synthesis

01 /Applications

Glycoconjugate Component

N-Acetylneuraminic acid is a key structural element in glycolipids, glycoproteins, and proteoglycans. Its presence is crucial for the specific binding properties exhibited by these complex biological molecules.

Biochemical Research

This compound is utilized to investigate the intricate biochemistry, metabolic pathways, and cellular uptake mechanisms of sialoglycoproteins both in vivo and in vitro.

Nanocarrier Development

N-Acetylneuraminic acid serves as a valuable component in the research and development of advanced nanocarrier systems, contributing to their design and functionality.

02 /Properties

Molecular weight	309.27
Empirical formula	C11H19NO9
Assay	≥98%
Form	synthetic, crystalline
Optical activity	[α]24/D −32.0°, c = 1 in H2O
Storage temperature	−20°C
Application	N-Acetylneuraminic acid (NANA, Neu5Ac) is a major component of glycoconjugates such as glycolipids, glycoproteins and proteoglycans (sialogylcoproteins) where it confers selective binding characteristics to the glycosylated component. Neu5Ac is used to study its biochemistry, metabolism and uptake in vivo and in vitro. Neu5Ac is used in the development of nanocarriers.
Melting point	184-186 °C (dec.)(lit.)

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

131-48-6

MDL number

MFCD00006620

PubChem substance

24888394

Beilstein registry

1716283

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is N-Acetylneuraminic acid (CAS: 131-48-6) primarily used for?

N-Acetylneuraminic acid is used to study its biochemistry, metabolism, and uptake in vivo and in vitro, and in the development of nanocarriers. It is a major component of glycoconjugates such as glycolipids, glycoproteins, and proteoglycans.

What are the CAS number and molecular formula for N-Acetylneuraminic acid?

The CAS number for N-Acetylneuraminic acid is 131-48-6, and its molecular formula is C11H19NO9.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies N-Acetylneuraminic acid with an assay of ≥98%. This product is intended for research purposes and is not represented as USP, BP, EP, or pharmaceutical grade.

How should N-Acetylneuraminic acid be handled and stored?

Handle N-Acetylneuraminic acid with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary. Store at −20°C.

Is N-Acetylneuraminic acid a controlled substance?

Based on the provided data, N-Acetylneuraminic acid (CAS: 131-48-6) is not indicated as a controlled substance.

How is N-Acetylneuraminic acid typically packed and exported?

N-Acetylneuraminic acid is typically supplied as a synthetic crystalline solid. TSS exports fine chemicals globally, adhering to all necessary regulations for safe and compliant shipment.