(−)-O,O′-Di-pivaloyl-L-tartaric acid
(−)-O,O′-Di-pivaloyl-L-tartaric acid (CAS 65259-81-6), with the empirical formula C14H22O8 and a molecular weight of 318.32, is a chiral organic compound. It serves as a valuable building block and reagent primarily in asymmetric synthesis. Its specific stereochemistry allows for the preparation of enantiomerically pure compounds, making it essential in fine chemical and pharmaceutical intermediate manufacturing. Available from Tech Serve Solutions.
- IUPAC
- (−)-DPTA
- Synonyms
- (−)-DPTA

Chiral Resolving Agent
This di-pivaloyl derivative of L-tartaric acid is frequently employed for the resolution of racemic mixtures. It forms diastereomeric salts or complexes with enantiomers, facilitating their separation through physical methods like crystallization.
Chiral Auxiliary in Asymmetric Synthesis
It can be used as a chiral auxiliary, temporarily incorporated into a molecule to direct stereoselective reactions. After the desired stereochemistry is established, the auxiliary is cleaved and can potentially be recovered.
Precursor for Chiral Ligands
The tartaric acid backbone, modified with bulky pivaloyl groups, makes it a suitable precursor for synthesizing specialized chiral ligands used in catalysis.
| Molecular weight | 318.32 |
|---|---|
| Empirical formula | C14H22O8 |
| Assay | ≥98.0% (T) |
| Optical activity | [α]20/D −23.5±1°, c = 1.7% in dioxane |
| Melting point | 127-132 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (−)-O,O′-Di-pivaloyl-L-tartaric acid used for?
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(−)-O,O′-Di-pivaloyl-L-tartaric acid is primarily used in asymmetric synthesis as a chiral resolving agent or a chiral auxiliary to produce enantiomerically pure compounds.
What is the CAS number and molecular formula for this compound?
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The CAS number is 65259-81-6, and its empirical formula is C14H22O8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (–)-O,O′-Di-pivaloyl-L-tartaric acid with an assay of ≥98.0% (T). We do not represent this product as USP, BP, or EP grade.
How should I handle (−)-O,O′-Di-pivaloyl-L-tartaric acid?
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Handle this compound with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used if dust is generated. Ensure adequate ventilation.
Is this product controlled or scheduled?
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There is no indication in the provided data that this substance is controlled or scheduled under common regulatory frameworks.
How is this chemical packed and exported?
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Products are typically packed according to industry standards for safe transport and are exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations.
How can I request a sample or obtain a quote?
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Please contact our sales team via the website or direct email to request a sample or obtain a quotation for this product.
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