O-tert-Butyl-L-serine
O-tert-Butyl-L-serine (CAS: 18822-58-7; Formula: C7H15NO3; MW: 161.20) is a protected amino acid derivative used in chemical synthesis and peptide chemistry. Its tert-butyl group provides a useful protecting group strategy for the serine side chain. This compound is valuable for researchers in chemical biology and organic synthesis requiring a stable, well-defined serine building block for complex molecule construction.
Peptide Synthesis
O-tert-Butyl-L-serine serves as a key building block in solid-phase and solution-phase peptide synthesis. The tert-butyl ester protects the carboxylic acid, facilitating controlled peptide chain elongation.
Chemical Biology Research
This compound is employed in studies investigating protein structure and function, or in the synthesis of modified peptides for biological assays. It allows for precise introduction of a protected serine residue into biomolecules.
Organic Synthesis
As a chiral building block, O-tert-Butyl-L-serine is utilised in the asymmetric synthesis of complex organic molecules and pharmaceutical intermediates where stereochemical control is paramount.
| Molecular weight | 161.20 |
|---|---|
| Empirical formula | C7H15NO3 |
| Assay | ≥97.0% (T) |
| Optical activity | [α]20/D −16.5±1°, c = 1% in H2O |
| Melting point | ~220 °C (dec.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-tert-Butyl-L-serine used for?
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O-tert-Butyl-L-serine is primarily used as a protected amino acid derivative in peptide synthesis and as a chiral building block in organic and chemical synthesis.
What are the CAS number and formula for O-tert-Butyl-L-serine?
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The CAS number for O-tert-Butyl-L-serine is 18822-58-7, and its empirical formula is C7H15NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-tert-Butyl-L-serine with an assay of ≥97.0% (T). This product is not represented as USP, BP, EP, or other pharmacopoeia grades.
What are the safety and handling precautions for O-tert-Butyl-L-serine?
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Handling O-tert-Butyl-L-serine requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or P1 (EN143) respirator filter is recommended. The compound is classified under WGK 2 in Germany.
How is O-tert-Butyl-L-serine typically shipped and exported?
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Tech Serve Solutions reliably exports and ships O-tert-Butyl-L-serine globally, adhering to all necessary regulations for chemical transport.
How can I request a sample or a quote for O-tert-Butyl-L-serine?
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To request a sample or a quote for O-tert-Butyl-L-serine, please contact our sales team through the website or by phone.
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