O-tert-Butyl-L-threonine
O-tert-Butyl-L-threonine (CAS 4378-13-6) is a valuable derivative of the amino acid threonine with the molecular formula C8H17NO3 and a molecular weight of 175.23 g/mol. This chiral compound is characterised by its specific optical rotation. It serves as a key building block in peptide synthesis and finds utility in various areas of chemical biology and advanced organic synthesis.
Peptide Synthesis
O-tert-Butyl-L-threonine is employed as a protected amino acid in solid-phase and solution-phase peptide synthesis. Its tert-butyl group offers a robust protecting strategy for the hydroxyl functionality during peptide chain elongation.
Chemical Biology Research
As an unnatural amino acid derivative, it can be incorporated into peptides or proteins to study structure-activity relationships or to create novel biomolecules with modified properties.
Organic Synthesis
The compound is utilised as a chiral synthon in the construction of complex organic molecules where stereochemical control is paramount.
| Molecular weight | 175.23 |
|---|---|
| Empirical formula | C8H17NO3 |
| Assay | ≥98.0% (T) |
| Optical activity | [α]20/D −43±2°, c = 1% in H2O |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-tert-Butyl-L-threonine used for?
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O-tert-Butyl-L-threonine is primarily used in peptide synthesis, chemical biology research, and as a chiral building block in organic synthesis.
What is the CAS number and formula for O-tert-Butyl-L-threonine?
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The CAS number is 4378-13-6, and the empirical formula is C8H17NO3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-tert-Butyl-L-threonine with an assay of ≥98.0% (T). This product is not supplied in USP, BP, or EP grade.
What are the safety and handling precautions for O-tert-Butyl-L-threonine?
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Appropriate personal protective equipment, including eyeshields and gloves, should be worn. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The substance has a WGK rating of 3 in Germany, indicating a high hazard to water.
How is O-tert-Butyl-L-threonine packed and shipped?
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Tech Serve Solutions exports fine chemicals globally. Please contact us for specific packaging and shipping details tailored to your location and order requirements.
How can I request a sample or quote for O-tert-Butyl-L-threonine?
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You can request a sample or obtain a quote by contacting our sales team directly through the details provided on our website.
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