O-[N-(6-Maleimidohexanoyl)aminoethyl]-O′-(2-carboxyethyl)polyethylene glycol
O-[N-(6-Maleimidohexanoyl)aminoethyl]-O′-(2-carboxyethyl)polyethylene glycol (CAS 948595-08-2) is a heterobifunctional PEG derivative. This compound features a carboxyl group at one end and a maleimide group at the other, linked by a polyethylene glycol chain with a molecular weight of approximately 3,000 Da. It is primarily utilised in bioconjugation, materials science, and chemical synthesis for linking molecules with different functionalities.
- Synonyms
- COOH-PEG-MaleimideMaleimide-PEG-COOH
![O-[N-(6-Maleimidohexanoyl)aminoethyl]-O′-(2-carboxyethyl)polyethylene glycol — chemical structure, CAS 948595-08-2; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F948595-08-2.png&w=3840&q=75)
Bioconjugation
This PEG derivative enables the covalent attachment of molecules containing thiol groups (via the maleimide) to molecules containing amine groups (via the carboxyl group after activation). This is useful for creating antibody-drug conjugates, protein labelling, and modifying surfaces.
Materials Science
It can be used to functionalise materials by introducing PEG chains, thereby modifying surface properties such as hydrophilicity, biocompatibility, and reducing non-specific protein adsorption.
Chemical Synthesis
As a building block, it allows for the controlled introduction of a PEG linker with distinct reactive ends into more complex molecular structures.
| Storage temperature | −20°C |
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| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Mol Wt | Mp 3,000 |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-[N-(6-Maleimidohexanoyl)aminoethyl]-O′-(2-carboxyethyl)polyethylene glycol used for?
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This compound is used in bioconjugation for linking molecules with different functional groups, in materials science for surface modification, and as a building block in chemical synthesis.
What are the CAS number and molecular formula?
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The CAS number is 948595-08-2. The molecular formula is not provided in the product data.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with a molecular weight of Mp 3,000. It is suitable for research purposes; TSS does not represent it as USP, BP, or EP grade.
What are the safety and handling precautions?
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Handle with care, using eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Refer to the Safety Data Sheet for full details. This compound has a WGK Germany rating of 3.
How is this chemical shipped and exported?
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This product is stored at -20°C and is exported globally by Tech Serve Solutions, a specialist supplier since 1998.
How can I request a sample or quote?
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Please contact our sales team via the website or by phone to request a sample or a quotation for this product.
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