O-tert-Butyl-L-serine tert-butyl ester hydrochloride
O-tert-Butyl-L-serine tert-butyl ester hydrochloride (CAS: 51537-21-4) is a protected amino acid derivative with the empirical formula C11H23NO3 · HCl and a molecular weight of 253.77 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in peptide chemistry and the development of novel chemical entities. Its protected nature facilitates controlled reactions in complex molecular assembly.

Peptide Synthesis
Utilised as a protected amino acid in solid-phase and solution-phase peptide synthesis, enabling controlled chain elongation and modification.
Organic Synthesis
Serves as a versatile intermediate for the construction of more complex organic molecules and heterocyclic compounds.
Chemical Biology Research
Employed in the synthesis of modified peptides and biomolecules for probing biological pathways and functions.
Pharmaceutical Intermediate
Acts as a key building block in the multi-step synthesis of active pharmaceutical ingredients (APIs).
| Molecular weight | 253.77 |
|---|---|
| Empirical formula | C11H23NO3 · HCl |
| Assay | ≥98.0% (AT) |
| Optical activity | [α]/D -10.0±1.0°, c = 1 in H2O |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is O-tert-Butyl-L-serine tert-butyl ester hydrochloride used for?
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This compound is primarily used as a protected amino acid derivative in peptide synthesis, organic synthesis, and chemical biology research. It also finds application as an intermediate in pharmaceutical synthesis.
What is the CAS number and formula for O-tert-Butyl-L-serine tert-butyl ester hydrochloride?
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The CAS number is 51537-21-4, and the empirical formula is C11H23NO3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies O-tert-Butyl-L-serine tert-butyl ester hydrochloride with an assay of ≥98.0% (AT). We do not represent this product as USP, BP, or EP grade.
How should O-tert-Butyl-L-serine tert-butyl ester hydrochloride be handled?
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Handle with appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The substance is classified with WGK 2 in Germany, indicating it is hazardous to water.
How is this chemical packed and exported?
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Tech Serve Solutions professionally packs and exports chemicals globally, adhering to international shipping regulations for hazardous materials.
How can I request a sample or quote?
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To request a sample or a quotation, please contact the Tech Serve Solutions sales team through our website or directly via email/phone.
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