(R)-(+)-N-Boc-2-piperidinecarboxylic acid
(R)-(+)-N-Boc-2-piperidinecarboxylic acid (CAS: 28697-17-8) is a chiral building block with the molecular formula C11H19NO4 and a molecular weight of 229.27 g/mol. This tert-butoxycarbonyl (Boc) protected amino acid derivative is valuable in organic synthesis, particularly within peptide chemistry and the development of unnatural amino acids. Its specific stereochemistry makes it a key intermediate for stereoselective reactions and the synthesis of complex chiral molecules.
- IUPAC
- (+)-N-Boc-(R)-pipecolinic acid,(R)-(+)-1-(tert-Butoxycarbonyl)-2-piperidinecarboxylic acid,(R)-N-Boc-piperidine-2-carboxylic acid,N-Boc-D-pipecolic acid,Boc-D-Pip-OH
- Synonyms
- (+)-N-Boc-(R)-pipecolinic acid(R)-(+)-1-(tert-Butoxycarbonyl)-2-piperidinecarboxylic acid(R)-N-Boc-piperidine-2-carboxylic acidN-Boc-D-pipecolic acidBoc-D-Pip-OH
Chiral Building Block in Organic Synthesis
Serves as a critical chiral synthon for constructing complex organic molecules, leveraging its defined stereochemistry. It is frequently employed in stereoselective synthesis pathways where precise molecular architecture is essential.
Peptide Chemistry
Utilised in the synthesis of peptides containing unnatural amino acid residues, enabling the creation of novel peptide structures with modified properties. Its Boc protection facilitates controlled peptide coupling reactions.
Development of Pharmaceutical Intermediates
Acts as a key intermediate in the multi-step synthesis of various pharmaceutical compounds. Its chiral nature is crucial for the development of stereospecific active pharmaceutical ingredients (APIs).
Chemical Biology Research
Applied in chemical biology for the design and synthesis of probes or modified biomolecules. This allows researchers to investigate biological processes with greater precision.
| Molecular weight | 229.27 |
|---|---|
| Empirical formula | C11H19NO4 |
| Assay | 98% |
| Optical activity | [α]23/D 63.5±3°, c = 1 in acetic acid |
| Optical purity | ee: 98% (GLC) |
| Melting point | 116-119 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-N-Boc-2-piperidinecarboxylic acid used for?
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This compound is primarily used as a chiral building block in organic synthesis, peptide chemistry, and in the development of pharmaceutical intermediates and for chemical biology research.
What are the CAS number and molecular formula of (R)-(+)-N-Boc-2-piperidinecarboxylic acid?
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The CAS number is 28697-17-8 and the molecular formula is C11H19NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-N-Boc-2-piperidinecarboxylic acid with a minimum assay of 98%. This product is intended for research and chemical synthesis purposes and is not supplied as USP, BP, EP, or pharmaceutical grade.
What are the primary hazards associated with this chemical?
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This compound is classified with a Warning signal word and carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used when handling it. Ensure adequate ventilation.
How is this chemical shipped and exported?
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As a specialist global supplier and exporter, Tech Serve Solutions is experienced in the safe and compliant shipping of fine chemicals worldwide. We adhere to all relevant international shipping regulations for chemical products.
How can I request a sample or a quote for (R)-(+)-N-Boc-2-piperidinecarboxylic acid?
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To request a sample or obtain a quote, please navigate to the product page and utilise the 'Request Sample' or 'Enquire' buttons, providing the necessary details for our sales team to assist you.
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