(R)-(+)-N-[1-(1-Naphthyl)ethyl]succinamic acid
(R)-(+)-N-[1-(1-Naphthyl)ethyl]succinamic acid (CAS 78681-09-1) is a chiral carboxylic acid with a molecular weight of 271.31. This compound serves as a valuable tool in asymmetric synthesis, primarily utilised as a chiral resolving agent for the separation of racemic amines. Its specific stereochemistry makes it effective in forming diastereomeric salts, facilitating the isolation of individual enantiomers in chemical synthesis and research applications.
![(R)-(+)-N-[1-(1-Naphthyl)ethyl]succinamic acid (C10H7CH(CH3)NHCOCH2CH2CO2H) — chemical structure, CAS 78681-09-1; Chemistry, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F78681-09-1.png&w=3840&q=75)
Chiral Resolution of Amines
This compound is employed as a chiral resolving agent to separate racemic mixtures of amines. It forms diastereomeric salts with amine enantiomers, allowing for their physical separation through techniques like fractional crystallisation.
Asymmetric Synthesis
As a chiral building block, it plays a role in asymmetric synthesis, contributing to the creation of enantiomerically pure compounds crucial for pharmaceutical and fine chemical industries.
Organic Synthesis
Utilised in general organic synthesis laboratories for its unique chiral properties, aiding in the development of stereoselective reactions and the synthesis of complex chiral molecules.
| Molecular weight | 271.31 |
|---|---|
| Linear formula | C10H7CH(CH3)NHCOCH2CH2CO2H |
| Assay | 98% |
| Optical activity | [α]24/D +45°, c = 2 in ethanol |
| Application | Acid for the resolution of amines.1,2 |
| Melting point | 157-159 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-N-[1-(1-Naphthyl)ethyl]succinamic acid used for?
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(R)-(+)-N-[1-(1-Naphthyl)ethyl]succinamic acid is primarily used as a chiral resolving agent for the separation of racemic amines in chemical synthesis and research.
What are the CAS number and formula for (R)-(+)-N-[1-(1-Naphthyl)ethyl]succinamic acid?
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The CAS number is 78681-09-1 and its linear formula is C10H7CH(CH3)NHCOCH2CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-N-[1-(1-Naphthyl)ethyl]succinamic acid at a minimum purity of 98%. We do not represent this product as USP, BP, or EP grade.
How should (R)-(+)-N-[1-(1-Naphthyl)ethyl]succinamic acid be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US recommended), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. It is classified as a warning substance with hazards including skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335).
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (R)-(+)-N-[1-(1-Naphthyl)ethyl]succinamic acid.
How can I request a sample or quote?
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Please contact our sales team via the website or by phone to request a sample or a quotation for (R)-(+)-N-[1-(1-Naphthyl)ethyl]succinamic acid.
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