(R)-(+)-Styrene oxide
(R)-(+)-Styrene oxide (CAS: 20780-53-4), with the chemical formula C8H8O and a molecular weight of 120.15 g/mol, is a chiral epoxide. It serves as a valuable building block in organic synthesis. Its primary application lies in the asymmetric synthesis of complex molecules, notably contributing to the production of homologated epoxides as an intermediate in the synthesis of compounds such as (+)-allosedamine. TSS supplies this chemical for research and development purposes.
- IUPAC
- (R)-(+)-Phenyloxirane,(R)-Phenylethylene oxide
- Synonyms
- (R)-(+)-Phenyloxirane(R)-Phenylethylene oxide
Asymmetric Synthesis
This chiral epoxide is utilised as a key intermediate in asymmetric synthesis. It enables the stereoselective construction of complex organic molecules by providing a defined chiral centre.
Production of Homologated Epoxides
The compound is employed in synthetic routes to produce homologated epoxides. These serve as precursors in the multi-step synthesis of target molecules like (+)-allosedamine.
Chiral Building Block
As a chiral building block, (R)-(+)-Styrene oxide is instrumental in introducing stereochemistry into organic structures. It is particularly useful in academic and industrial research for developing novel synthetic methodologies.
| Molecular weight | 120.15 |
|---|---|
| Empirical formula | C8H8O |
| Assay | 98% |
| Boiling point | 89-90 °C/23 mmHg(lit.) |
| Density | 1.051 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.534(lit.) |
| Optical activity | [α]18/D +33°, neat |
| Optical purity | ee: 95% (HPLC) |
| Autoignition temp | 928 °F |
| Storage temperature | 2-8°C |
| Application | Used to produce a homologated epoxide as part of a synthetic approach to (+)-allosedamine.1 |
Hazard statements
- H312Harmful in contact with skin
- H319Causes serious eye irritation
- H350May cause cancer
Precautionary statements
- P201Obtain special instructions before use
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P308IF exposed or concerned
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 80 °C / 176 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 45-21-36 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-Styrene oxide used for?
+
It is used in asymmetric synthesis, particularly for producing homologated epoxides as intermediates in the synthesis of compounds such as (+)-allosedamine.
What is the CAS number and chemical formula for (R)-(+)-Styrene oxide?
+
(R)-(+)-Styrene oxide has the CAS number 20780-53-4 and the chemical formula C8H8O.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies (R)-(+)-Styrene oxide with an assay of 98% and optical purity of ee: 95% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeia grades.
How should (R)-(+)-Styrene oxide be handled safely?
+
This compound is classified as a Danger with hazards including H312 (Harmful in contact with skin), H319 (Causes serious eye irritation), and H350 (May cause cancer). Appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, must be worn. Handle in a well-ventilated area and avoid exposure.
How is (R)-(+)-Styrene oxide packed and shipped?
+
This chemical is shipped according to ADR regulations as NA 1993 / PGIII. Storage is recommended at 2-8°C.
How can I request a sample or quote for (R)-(+)-Styrene oxide?
+
To request a sample or a quote, please contact the TSS sales department through our website or by phone, providing the product name and CAS number (20780-53-4).
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