(R)-(+)-N-(1-Phenylethyl)succinamic acid
(R)-(+)-N-(1-Phenylethyl)succinamic acid (CAS: 21752-33-0) is a chiral organic compound with the linear formula C6H5CH(CH3)NHCOCH2CH2CO2H and a molecular weight of 221.25 g/mol. This carboxylic acid serves as a valuable chiral resolving agent, particularly for the separation of racemic amine mixtures. Its specific stereochemistry makes it a key building block in asymmetric synthesis, enabling the production of enantiomerically pure compounds for various chemical and pharmaceutical applications.
- IUPAC
- (R)-(+)-N-(α-Methylbenzyl)succinamidic acid
- Synonyms
- (R)-(+)-N-(α-Methylbenzyl)succinamidic acid
Chiral Resolution of Amines
This compound is effectively employed as an acidic chiral resolving agent for the separation of racemic amines. By forming diastereomeric salts, it facilitates the isolation of individual enantiomers.
Asymmetric Synthesis
As a chiral building block, (R)-(+)-N-(1-Phenylethyl)succinamic acid is instrumental in asymmetric synthesis. It contributes to the stereoselective construction of complex molecules, crucial in pharmaceutical development.
Organic Synthesis Intermediate
The molecule's functional groups make it a versatile intermediate in broader organic synthesis pathways. It can be used in the preparation of various functionalised organic compounds.
| Molecular weight | 221.25 |
|---|---|
| Linear formula | C6H5CH(CH3)NHCOCH2CH2CO2H |
| Assay | 98% |
| Optical activity | [α]24/D +111°, c = 2 in ethanol |
| Application | Acid for the resolution of amines.1,2 |
| Melting point | 100-104 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-N-(1-Phenylethyl)succinamic acid used for?
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(R)-(+)-N-(1-Phenylethyl)succinamic acid is primarily used as a chiral resolving agent for the separation of racemic amines and as a chiral building block in asymmetric synthesis.
What are the CAS number and formula for this compound?
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The CAS number is 21752-33-0 and the linear formula is C6H5CH(CH3)NHCOCH2CH2CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound at a purity of 98%. It is not specified as USP, BP, or EP grade; it is supplied as a research or technical grade chemical.
What are the safety and handling considerations for this chemical?
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This compound is a warning irritant, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, should be used. Handle in a well-ventilated area.
How is (R)-(+)-N-(1-Phenylethyl)succinamic acid packed and exported?
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Tech Serve Solutions, being a specialist global supplier and exporter, ensures appropriate packing and export procedures for all its chemicals, including (R)-(+)-N-(1-Phenylethyl)succinamic acid, adhering to international shipping regulations.
How can I request a sample or quote?
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To request a sample or a quote for (R)-(+)-N-(1-Phenylethyl)succinamic acid, please contact our sales department via the website or your dedicated account manager.
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