2-Thienylzinc bromide solution
2-Thienylzinc bromide solution (CAS 45438-80-0, C4H3BrSZn, MW 228.43) is an organozinc reagent supplied by Tech Serve Solutions at 0.5 M in THF. This chemical is primarily utilised in organic synthesis as a versatile building block. It plays a key role in cross-coupling reactions, enabling the introduction of the 2-thienyl moiety into various molecular structures, facilitating the development of complex organic compounds for research and industrial applications.
Organometallic Cross-Coupling
Serves as a nucleophilic coupling partner in various metal-catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Negishi couplings. This allows for the efficient formation of carbon-carbon bonds with aryl or vinyl halides.
Heteroaryl Synthesis
Enables the regioselective introduction of the 2-thienyl group into organic molecules. This is particularly useful in the synthesis of thiophene-containing compounds with applications in materials science and medicinal chemistry.
Precursor for Complex Molecules
Acts as a valuable intermediate in multi-step syntheses of pharmaceuticals, agrochemicals, and advanced materials requiring a thiophene core.
| Molecular weight | 228.43 |
|---|---|
| Empirical formula | C4H3BrSZn |
| Density | 0.973 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Thienylzinc bromide solution used for?
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2-Thienylzinc bromide solution is primarily used in organic synthesis for cross-coupling reactions and the introduction of the 2-thienyl moiety into complex molecules.
What is the CAS number and formula for 2-Thienylzinc bromide solution?
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The CAS number is 45438-80-0 and the empirical formula (Hill notation) is C4H3BrSZn.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Thienylzinc bromide solution at a concentration of 0.5 M in THF. TSS does not represent this product as USP, BP, or EP grade.
How should 2-Thienylzinc bromide solution be handled and stored?
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This solution is flammable (H225) and may form explosive peroxides. It can cause serious eye irritation (H319) and respiratory irritation (H335), and is suspected of causing cancer (H351). Handle in a well-ventilated area away from ignition sources, wearing appropriate personal protective equipment. Store refrigerated at 2-8°C and check for peroxide formation.
Is 2-Thienylzinc bromide solution shipped internationally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote for 2-Thienylzinc bromide solution?
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Please contact our sales team via the website or your dedicated account manager to request a sample or a quotation for 2-Thienylzinc bromide solution.
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