2-Thienylmagnesium bromide solution
2-Thienylmagnesium bromide solution (CAS 5713-61-1) is an organometallic reagent with the empirical formula C4H3BrMgS and a molecular weight of 187.34 g/mol. Supplied as a 1.0 M solution in THF, this Grignard reagent is a valuable tool in organic synthesis, particularly for the introduction of the 2-thienyl moiety into various organic molecules. Its reactivity makes it suitable for a range of coupling and addition reactions in chemical research and development.
Heteroaryl Synthesis
Utilised in organic synthesis for the regioselective introduction of the 2-thienyl group into complex molecular structures. This is crucial for building novel heterocyclic compounds used in pharmaceuticals and materials science.
Grignard Reagent Chemistry
Serves as a versatile nucleophile in Grignard reactions, enabling the formation of new carbon-carbon bonds with electrophiles such as aldehydes, ketones, and esters.
Organometallic Coupling Reactions
Employed in transition-metal catalysed cross-coupling reactions to synthesise substituted thiophenes and other organosulfur compounds relevant to medicinal chemistry.
| Molecular weight | 187.34 |
|---|---|
| Empirical formula | C4H3BrMgS |
| Boiling point | 65 °C |
| Density | 1.011 g/mL at 25 °C |
| Concentration | 1.0 M in THF |
Hazard statements
- H225Highly flammable liquid and vapour
- H319Causes serious eye irritation
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P281Use personal protective equipment as required
- P305IF IN EYES
| Flash point | -21 °C / -5.8 °F |
|---|---|
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,Xn |
| Risk statements (R) | 11-19-36/37-40 |
| Safety statements (S) | 16-26-36/37 |
| Supplemental hazards | May form explosive peroxides. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Thienylmagnesium bromide solution used for?
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2-Thienylmagnesium bromide solution is primarily used in organic synthesis as a Grignard reagent for introducing the 2-thienyl moiety into other molecules, facilitating the construction of complex heteroaryl compounds.
What is the CAS number and formula for 2-Thienylmagnesium bromide solution?
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The CAS number is 5713-61-1, and the empirical formula is C4H3BrMgS.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Thienylmagnesium bromide solution at a concentration of 1.0 M in THF. It is a research-grade chemical, and we do not represent it as USP, BP, EP, or any other pharmacopoeial standard.
How should 2-Thienylmagnesium bromide solution be handled safely?
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This solution is flammable and can cause serious eye irritation and respiratory irritation. It may also be associated with cancer risks. It may form explosive peroxides. Handle with appropriate personal protective equipment in a well-ventilated area, away from ignition sources. Refer to the Safety Data Sheet (SDS) for full details.
How is 2-Thienylmagnesium bromide solution packed and shipped?
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2-Thienylmagnesium bromide solution is packed in UN-approved containers and shipped according to international regulations for hazardous materials. It is classified under UN 2924, Class 8(3), Packing Group II.
How can I request a sample or quote for 2-Thienylmagnesium bromide solution?
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To request a sample or a detailed quote, please contact our sales department via email or phone, providing your specific requirements and delivery information.
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