2-Thiazolylzinc bromide solution
2-Thiazolylzinc bromide solution (CAS: 173382-28-0; C3H2BrNSZn; MW: 229.41) is a valuable organozinc reagent. Supplied as a 0.5 M solution in THF, it is a reactive intermediate crucial for introducing the 2-thiazolyl moiety into organic molecules. Its primary applications lie in complex molecule synthesis, particularly in the development of pharmaceuticals and agrochemicals, where the thiazole ring is a common structural motif.
Cross-Coupling Reactions
Serves as a key nucleophilic partner in transition metal-catalyzed cross-coupling reactions, such as Negishi couplings, for C-C bond formation.
Heterocyclic Synthesis
Facilitates the synthesis of diverse heterocycles containing the thiazole ring, a structure prevalent in many biologically active compounds.
Pharmaceutical Intermediate
Used in the synthetic routes for various pharmaceutical agents where the 2-thiazolyl group is an integral part of the drug molecule.
Agrochemical Development
Enables the construction of novel agrochemical compounds incorporating the 2-thiazolyl scaffold.
| Molecular weight | 229.41 |
|---|---|
| Empirical formula | C3H2BrNSZn |
| Density | 0.992 g/mL at 25 °C |
| Concentration | 0.5 M in THF |
| Storage temperature | 2-8°C |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
- H351Suspected of causing cancer
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | -17 °C / 1.4 °F |
|---|---|
| Transport (UN / ADR) | UN 2056 3 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-14-19-34-37-40 |
| Safety statements (S) | 16-26-36/37/39-45 |
| Supplemental hazards | May form explosive peroxides., Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Thiazolylzinc bromide solution used for?
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2-Thiazolylzinc bromide solution is primarily used as a reagent in organic synthesis, particularly for introducing the 2-thiazolyl group via cross-coupling reactions and for the synthesis of heterocyclic compounds.
What is the CAS number and formula for 2-Thiazolylzinc bromide solution?
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The CAS number for 2-Thiazolylzinc bromide solution is 173382-28-0, and its empirical formula (Hill notation) is C3H2BrNSZn.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Thiazolylzinc bromide solution at a concentration of 0.5 M in THF. We do not represent this product as USP/BP/EP grade.
How should 2-Thiazolylzinc bromide solution be handled safely?
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This solution is highly flammable and reacts violently with water. It can cause severe skin burns and eye damage, and may cause respiratory irritation and is suspected of causing cancer. Handle with extreme caution in a well-ventilated area, wearing appropriate personal protective equipment (gloves, eye protection, lab coat), and avoid contact with water, air, and incompatible materials.
How is 2-Thiazolylzinc bromide solution shipped and exported?
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2-Thiazolylzinc bromide solution is shipped under UN 2056, Hazard Class 3, Packing Group II, meeting stringent international regulations for hazardous material transport. TSS is an experienced global exporter.
How can I request a sample or quote for 2-Thiazolylzinc bromide solution?
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Please contact our sales department via the website or by phone to request a sample or a formal quotation for 2-Thiazolylzinc bromide solution.
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