(R)-(+)-N,α-Dimethylbenzylamine
(R)-(+)-N,α-Dimethylbenzylamine (CAS 5933-40-4) is a chiral amine with the linear formula C₆H₅CH(CH₃)NHCH₃ and a molecular weight of 135.21 g/mol. This optically active compound serves as a valuable building block in asymmetric synthesis and chiral resolution processes. Its specific stereochemistry makes it crucial for stereoselective reactions, enabling the synthesis of complex enantiopure molecules in pharmaceutical and fine chemical industries.
- IUPAC
- (R)-(+)-N-Methyl-1-phenylethylamine
- Synonyms
- (R)-(+)-N-Methyl-1-phenylethylamine(R)-1-(Methylamino)-1-phenylethane
Chiral Resolving Agent
Used to separate racemic mixtures into individual enantiomers. Its specific R-configuration allows for differential interactions with target molecules, facilitating the isolation of desired stereoisomers.
Asymmetric Synthesis
Acts as a chiral auxiliary or building block in stereoselective synthesis. It can be incorporated into molecules to direct the stereochemical outcome of subsequent reactions.
Pharmaceutical Intermediates
Serves as a key intermediate in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs). Its chiral nature is essential for developing drugs with specific biological activities.
Research and Development
Employed in academic and industrial research labs for exploring novel synthetic methodologies and developing new chiral compounds.
| Molecular weight | 135.21 |
|---|---|
| Linear formula | C6H5CH(CH3)NHCH3 |
| Assay | ≥96.0% (sum of enantiomers, GC) |
| Grade | purum |
| Boiling point | 74-76 °C/11 mmHg(lit.) |
| Density | 0.924 g/mL at 20 °C(lit.) |
| Refractive index | n20/D 1.511(lit.)n20/D 1.511 |
| Optical activity | [α]20/D +74±4°, c = 2% in chloroform |
Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H314Causes severe skin burns and eye damage
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 61 °C / 141.8 °F |
| Transport (UN / ADR) | UN 2619 3(8) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 20/21/22-34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-N,α-Dimethylbenzylamine used for?
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(R)-(+)-N,α-Dimethylbenzylamine is primarily used as a chiral resolving agent and a building block in asymmetric synthesis, particularly in the development of pharmaceutical intermediates and other enantiomerically pure compounds.
What is the CAS number and chemical formula for (R)-(+)-N,α-Dimethylbenzylamine?
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The CAS number is 5933-40-4, and its linear chemical formula is C₆H₅CH(CH₃)NHCH₃.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-N,α-Dimethylbenzylamine with a grade of 'purum' and an assay of ≥96.0% (sum of enantiomers, GC). We do not represent this product as USP, BP, or EP grade.
How should (R)-(+)-N,α-Dimethylbenzylamine be handled safely?
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This compound is classified as corrosive and harmful if swallowed, inhaled, or in contact with skin (H302-H312-H314-H332). Handling requires appropriate personal protective equipment, including gloves, goggles, and respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for full details.
Is (R)-(+)-N,α-Dimethylbenzylamine a controlled substance?
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Based on the provided data, (R)-(+)-N,α-Dimethylbenzylamine is not indicated as a controlled substance. However, users should always verify local regulations.
How can I request a sample or quote for (R)-(+)-N,α-Dimethylbenzylamine?
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To request a sample or a quote, please use the contact form on our website or reach out to our sales team directly. Provide the product name or CAS number for prompt service.
How is (R)-(+)-N,α-Dimethylbenzylamine packed, shipped, and exported?
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(R)-(+)-N,α-Dimethylbenzylamine is packed according to relevant regulations for hazardous materials. We offer global export services, adhering to all international shipping and customs requirements.
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