(R)-(+)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine
(R)-(+)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine (CAS 161583-25-1) is a chiral phosphine ligand with a molecular weight of 545.63 g/mol. This compound is instrumental in asymmetric synthesis and is utilized as a chiral catalyst or ligand in various chemical transformations. Its specific stereochemistry makes it valuable for enantioselective reactions in organic chemistry and pharmaceutical intermediate synthesis.
- IUPAC
- (R)-(+)-N,N-Bis(2-diphenylphosphinoethyl)-α-methylbenzylamine
- Synonyms
- (R)-(+)-N,N-Bis(2-diphenylphosphinoethyl)-α-methylbenzylamine
Asymmetric Catalysis
This chiral phosphine ligand is employed as a crucial component in transition metal catalysts for enantioselective reactions. It facilitates the stereocontrolled synthesis of chiral molecules, essential for pharmaceuticals and fine chemicals.
Ligand in Organic Synthesis
As a sophisticated ligand, it coordinates with metal centers to influence reaction pathways and selectivity. Its structure is designed to promote high enantiomeric excess in catalytic processes such as hydrogenations and C-C bond formations.
Chiral Reagent
It serves as a specialised reagent in academic research and industrial process development for creating enantiomerically pure compounds. Its application is key in producing single-enantiomer drugs and complex organic molecules.
| Molecular weight | 545.63 |
|---|---|
| Empirical formula | C36H37NP2 |
| Assay | ≥98.0% (CHN) |
| Optical activity | [α]20/D +4.5±0.7°, c = 1% in acetone |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3259 8/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (R)-(+)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine used for?
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(R)-(+)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine is primarily used as a chiral ligand or catalyst in asymmetric synthesis, facilitating the enantioselective creation of complex organic molecules.
What are the CAS number and molecular formula for this compound?
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The CAS number is 161583-25-1 and the empirical formula (Hill Notation) is C36H37NP2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies (R)-(+)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine with an assay of ≥98.0% (CHN). This is a research or technical grade material, and TSS does not represent it as USP, BP, or EP grade.
How should (R)-(+)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine be handled?
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This compound is classified as corrosive (H314), causing severe skin burns and eye damage. Appropriate personal protective equipment, including eyeshields, face shields, gloves, and respiratory protection, must be used. Handle only in well-ventilated areas. Refer to the Safety Data Sheet for detailed handling instructions.
Is this chemical packed and shipped internationally by TSS?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including (R)-(+)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine, and can arrange international shipments.
How can I request a sample or a quote for this chemical?
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To request a sample or a quote for (R)-(+)-N,N-Bis(2-diphenylphosphinoethyl)-1-phenylethylamine, please contact our sales team through the website or by phone, providing your specific requirements.
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