JKC 302

CAS 153982-38-8C30H42N6O6Biochemicals & Reagents

JKC 302 (CAS: 153982-38-8), a cyclic peptide with the formula C30H42N6O6 and a molecular weight of 582.69 g/mol, functions as an endothelin receptor antagonist. This biochemical reagent is valuable for research in cell biology, particularly in studies involving cell signalling and neuroscience. Its specific mechanism of action relates to GPCR modulation, making it a useful tool for investigating these complex biological pathways in laboratory settings.

IUPAC: cyclo(D-Ser-Pro-D-Val-Leu-D-Trp)

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JKC 302 (C30H42N6O6) — chemical structure, CAS 153982-38-8; Life Science, fine chemical supplied by Tech Serve Solutions

AntagonistsBiochemicals and ReagentsCell BiologyEndothelinsGPCR ModulatorsGPCR ProteinsModulators and AntibodiesPeptides and ProteinsPeptides for Cell Biology

01 /Applications

Endothelin Receptor Antagonism Research

JKC 302 serves as a specific antagonist for endothelin receptors, enabling researchers to investigate the physiological roles of endothelin signalling pathways in vitro. This is crucial for understanding conditions influenced by endothelin, such as cardiovascular and neurological disorders.

Cell Signalling and Neuroscience Studies

As a modulator of GPCRs, JKC 302 is employed in cell signalling research, particularly within neuroscience. It aids in elucidating the complex mechanisms underlying neuronal communication and function by blocking specific receptor interactions.

Biochemical Reagent for Laboratory Use

This compound is supplied as a high-purity biochemical reagent suitable for advanced laboratory applications. Its well-defined structure and activity make it a reliable tool for academic and industrial research in molecular and cell biology.

02 /Properties

Molecular weight	582.69
Empirical formula	C30H42N6O6
Assay	≥97% (HPLC)
Storage temperature	−20°C

03 /Safety & handling

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

153982-38-8

MDL number

MFCD00270699

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is JKC 302 used for?

JKC 302 is used as a research chemical, specifically functioning as an endothelin receptor antagonist and a GPCR modulator, valuable in cell biology, cell signalling, and neuroscience studies.

What are the CAS number and formula for JKC 302?

The CAS number for JKC 302 is 153982-38-8, and its molecular formula is C30H42N6O6.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies JKC 302 with an assay of ≥97% (HPLC). TSS does not represent this product as USP, BP, EP, or other pharmacopoeial grades.

What are the safety and handling recommendations for JKC 302?

When handling JKC 302, appropriate personal protective equipment including eyeshields and gloves is essential. A type N95 (US) or type P1 (EN143) respirator filter should be used. The compound has a WGK Germany rating of 3, indicating significant hazard.

How is JKC 302 stored and shipped?

JKC 302 should be stored at -20°C. Tech Serve Solutions exports fine chemicals globally, adhering to all necessary shipping regulations for research-grade compounds.

How can I request a sample or quote for JKC 302?

To request a sample or a quote for JKC 302, please contact our sales department through the website or direct email, providing your specific requirements and delivery details.