JNJ7777120
JNJ7777120 (CAS: 459168-41-3), with the molecular formula C14H16N3OCl and a molecular weight of 277.75 g/mol, is a white to off-white solid. This compound functions as a potent antagonist, primarily investigated for its role in modulating biological pathways. Its applications are centred around research in cell biology, neuroscience, and GPCR-related signalling, making it a valuable reagent for scientific inquiry.
- IUPAC
- 1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine

Neuroscience Research
JNJ7777120 serves as a valuable tool in neuroscience research, particularly for studying cell signaling pathways and their role in neurological functions. Its antagonist properties are instrumental in dissecting complex biological mechanisms.
GPCR Modulation Studies
As a GPCR modulator, this compound is used to investigate the function and regulation of G protein-coupled receptors. This aids in understanding receptor-mediated signalling cascades relevant to various physiological processes.
Drug Discovery and Development
Identified as a potential drug candidate, JNJ7777120 is of interest in early-stage drug discovery. Its activity against specific biological targets makes it a subject of investigation for therapeutic applications.
Cell Biology Investigations
This molecule is employed in cell biology research to probe cellular responses and signaling networks. Its use helps researchers elucidate intracellular communication and metabolic pathways.
| Molecular weight | 277.75 |
|---|---|
| Empirical formula | C14H16N3OCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | DMSO: >20 mg/mLH2O: insoluble |
| Storage temperature | room temp |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is JNJ7777120 used for?
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JNJ7777120 is utilised in research for its antagonist properties, particularly in studies involving neuroscience, GPCR modulation, and cell biology. It is also recognised as a potential therapeutic drug candidate.
What are the CAS number and formula for JNJ7777120?
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The CAS number for JNJ7777120 is 459168-41-3, and its molecular formula is C14H16N3OCl.
What grade and purity does Tech Serve Solutions supply for JNJ7777120?
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Tech Serve Solutions supplies JNJ7777120 with a purity of ≥98% (HPLC). This product is supplied for research and development purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should JNJ7777120 be handled and stored?
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JNJ7777120 is classified as a Warning substance (GHS07) with hazards H315, H319, and H335. Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Store at room temperature. Avoid dust formation and inhalation.
Is JNJ7777120 shipped or exported internationally?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including JNJ7777120, and can accommodate international shipping requests.
How can I request a sample or quote for JNJ7777120?
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To request a sample or a quotation for JNJ7777120, please contact our sales department through the TSS website or via email, providing your specific requirements.
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