K-252a

CAS 99533-80-9C27H21N3O5Biochemicals & Reagents

K-252a (CAS 99533-80-9), a C27H21N3O5 molecule with a molecular weight of 467.47, is a biologically active compound isolated from Nonomuraea longicatena. It functions as a potent inhibitor of protein kinases. K-252a is recognised for its role in cellular signalling research and neurobiology, particularly in studies involving protein kinase A, C, and G. This compound is shipped under dry ice conditions to maintain its integrity for research applications.

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K-252a (C27H21N3O5) — chemical structure, CAS 99533-80-9; Life Science, fine chemical supplied by Tech Serve Solutions

AntibioticsAntibiotics A to ZAntibiotics G-MAntibiotics by ApplicationAntiviralBioactive Small MoleculesBiochemicals and ReagentsCell BiologyKinase/Phosphatase BiologyProtein Kinase A

01 /Applications

Protein Kinase Inhibition Research

K-252a is widely utilised as an inhibitor of protein kinases, including Protein Kinase A, C, and G. It serves as a critical tool in understanding cellular signalling pathways and the mechanisms of kinase-dependent biological processes.

Cellular Signalling and Neuroscience Studies

This compound plays a significant role in research related to cell signalling and neuroscience. Its ability to modulate kinase activity makes it valuable for investigating neuronal development, function, and disease mechanisms.

Antiviral Research

K-252a has demonstrated antiviral properties. It is employed in laboratory settings to investigate the potential of kinase inhibitors in the development of antiviral therapies.

Biochemical and Reagent Use

As a well-characterised biochemical reagent, K-252a is supplied for various in vitro research applications. Its defined properties make it suitable for standardisation and comparative studies in biological assays.

02 /Properties

Molecular weight	467.47
Empirical formula	C27H21N3O5
Storage temperature	−20°C
Biological source	from Nonomuraea longicatena

03 /Safety & handling

Precautionary statements

P201Obtain special instructions before use
P260Do not breathe dust, fume, gas, mist, vapours or spray
P308IF exposed or concerned

Protective equipment	Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
Water hazard class (WGK, DE)	3

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

99533-80-9

MDL number

MFCD00161522

PubChem substance

24896210

05 /Additional specifications

Shipped In	dry ice
Gene Information	human ... NTRK1(4914)rat ... Prkca(24680)

06 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

07 /Frequently asked questions

What is K-252a used for?

K-252a is primarily used as a potent inhibitor of protein kinases, making it valuable in research for studying cellular signalling pathways, neuroscience, and as an antiviral agent.

What is the CAS number and formula for K-252a?

The CAS number for K-252a is 99533-80-9 and its molecular formula is C27H21N3O5.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies K-252a as a research-grade chemical. The specific assay or purity is detailed in the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade.

What are the safety and handling precautions for K-252a?

K-252a requires careful handling. Recommended personal protective equipment includes eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. It has a WGK Germany rating of 3, indicating it is hazardous. Users should follow precautionary statements P201, P260, and P308 + P313.