2,4,5-Trifluorophenylboronic acid
2,4,5-Trifluorophenylboronic acid (CAS 247564-72-3) is a versatile organoboron compound with the linear formula F3C6H2B(OH)2 and a molar mass of 175.90 g/mol. It serves as a key building block in organic synthesis, particularly in metal-catalysed cross-coupling reactions. Its unique trifluorinated phenyl structure makes it valuable for introducing specific fluorinated motifs into complex molecules, finding utility in the development of advanced materials and pharmaceutical intermediates.
- Synonyms
- 247564-72-3F3C6H2B(OH)2
Suzuki-Miyaura Coupling Reagent
2,4,5-Trifluorophenylboronic acid is a primary reactant in Suzuki-Miyaura cross-coupling reactions. This palladium-catalysed process is widely employed for the formation of carbon-carbon bonds, enabling the synthesis of biaryl compounds and other complex organic structures.
Intermediate in Organic Synthesis
This boronic acid derivative acts as a crucial intermediate in multi-step organic syntheses. Its trifluorinated phenyl moiety can be incorporated into target molecules, influencing properties such as lipophilicity, metabolic stability, and binding affinity in pharmaceutical and agrochemical research.
Building Block for Fluorinated Compounds
The compound is utilized for the precise introduction of the 2,4,5-trifluorophenyl group. This is particularly relevant in the design and synthesis of novel fluorinated organic materials and biologically active compounds where fluorine substitution can modulate key characteristics.
| Molecular weight | 175.90 |
|---|---|
| Linear formula | F3C6H2B(OH)2 |
| Application | Reactant for:• Suzuki-Miyaura coupling1,2 |
| Melting point | 100 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4,5-Trifluorophenylboronic acid used for?
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2,4,5-Trifluorophenylboronic acid is primarily used as a reactant in Suzuki-Miyaura coupling reactions and as a building block for introducing the 2,4,5-trifluorophenyl group into complex organic molecules, particularly in the development of pharmaceuticals and advanced materials.
What is the CAS number and chemical formula for 2,4,5-Trifluorophenylboronic acid?
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The CAS number is 247564-72-3 and the linear chemical formula is F3C6H2B(OH)2.
What grade and purity does Tech Serve Solutions supply for 2,4,5-Trifluorophenylboronic acid?
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Tech Serve Solutions supplies 2,4,5-Trifluorophenylboronic acid for research and chemical synthesis purposes. We do not represent this product as USP, BP, EP or any other pharmacopoeia grade. Purity information is available upon request and may vary by batch.
What are the safety and handling recommendations for 2,4,5-Trifluorophenylboronic acid?
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Handling 2,4,5-Trifluorophenylboronic acid requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. Consult the Safety Data Sheet (SDS) for comprehensive hazard information and handling procedures.
Is 2,4,5-Trifluorophenylboronic acid a controlled substance?
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Based on the provided data, there is no indication that 2,4,5-Trifluorophenylboronic acid is a controlled substance. However, regulations can vary by jurisdiction, and users should verify compliance with local laws.
How is 2,4,5-Trifluorophenylboronic acid packed and shipped?
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2,4,5-Trifluorophenylboronic acid is packed securely to maintain its integrity during transit. Tech Serve Solutions exports chemicals globally, adhering to international shipping regulations for hazardous materials where applicable.
How can I request a quote or sample for 2,4,5-Trifluorophenylboronic acid?
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To request a quote or a sample of 2,4,5-Trifluorophenylboronic acid, please contact our sales department through the website or by phone. Our team will be happy to assist you with your inquiry.
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