7-Aminocephalosporanic acid
7-Aminocephalosporanic acid (7-ACA), CAS 957-68-6, with the molecular formula C10H12N2O5S and a molecular weight of 272.28 g/mol, is a key intermediate in the synthesis of semi-synthetic cephalosporin antibiotics. It serves as a crucial building block, enabling the development of various antibacterial agents that combat a range of bacterial infections. This compound is essential for research and development in pharmaceutical chemistry and drug discovery.
- IUPAC
- 7-ACA
Antibiotic Synthesis
7-ACA is a foundational precursor for the production of numerous semi-synthetic cephalosporin antibiotics. Its chemical structure allows for modifications to create potent antibacterial agents.
Pharmaceutical Intermediate
As a vital intermediate, 7-ACA plays a critical role in the multi-step synthesis pathways of advanced pharmaceutical compounds. It is integral to drug development processes.
Research and Development
This compound is utilised in research laboratories for exploring new antibiotic derivatives and understanding mechanisms of antibacterial action. It supports innovation in medicinal chemistry.
Beta-Lactamase Inhibition Studies
7-ACA is recognised for its role in studies related to beta-lactamase, an enzyme that confers bacterial resistance to beta-lactam antibiotics. It can act as a potent inhibitor.
| Molecular weight | 272.28 |
|---|---|
| Empirical formula | C10H12N2O5S |
| Assay | ≥95% (HPLC) |
| Storage temperature | 2-8°C |
| Application | Potent inhibitor of bacterial (S. aureus) β-lactamase.1 |
| Melting point | >300 °C(lit.) |
Hazard statements
- H317May cause an allergic skin reaction
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P342
| Protective equipment | dust mask type N95 (US), Eyeshields, Faceshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 42/43 |
| Safety statements (S) | 22-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 7-Aminocephalosporanic acid used for?
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7-Aminocephalosporanic acid (7-ACA) is primarily used as a key intermediate in the synthesis of semi-synthetic cephalosporin antibiotics and in pharmaceutical research and development.
What is the CAS number and chemical formula for 7-Aminocephalosporanic acid?
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The CAS number for 7-Aminocephalosporanic acid is 957-68-6, and its chemical formula is C10H12N2O5S.
What grade and purity does Tech Serve Solutions supply for 7-Aminocephalosporanic acid?
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Tech Serve Solutions supplies 7-Aminocephalosporanic acid with a purity of ≥95% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should 7-Aminocephalosporanic acid be handled safely?
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Handling 7-Aminocephalosporanic acid requires caution due to potential respiratory and skin sensitisation. Use a dust mask (type N95 or equivalent), eyeshields, face shields, and gloves. Ensure good ventilation and avoid breathing dust. P261, P280, P342 + P311.
How is 7-Aminocephalosporanic acid packed and shipped?
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7-Aminocephalosporanic acid is typically stored at 2-8°C. TSS exports this chemical globally, adhering to all necessary shipping and handling regulations for chemical compounds.
How can I request a sample or quote for 7-Aminocephalosporanic acid?
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To request a sample or a quote for 7-Aminocephalosporanic acid, please contact our sales team through the website or provide your details via the contact form.
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