2,4,5-Trifluorophenyl isocyanate
2,4,5-Trifluorophenyl isocyanate (CAS: 932710-67-3) is a fluorinated organic building block with the molecular formula C7H2F3NO and a molecular weight of 173.09 g/mol. This compound serves as a valuable intermediate in chemical synthesis. Its trifluorophenyl structure offers unique reactivity, making it suitable for incorporation into more complex molecules within research and development settings, particularly in the fields of materials science and medicinal chemistry.
- Synonyms
- 932710-67-3C7H2F3NO
Organic Synthesis Intermediate
2,4,5-Trifluorophenyl isocyanate is utilised as a reactive intermediate in the synthesis of various organic compounds. Its isocyanate functional group readily reacts with nucleophiles, enabling the formation of amides, ureas, and carbamates, which are common motifs in pharmaceuticals and agrochemicals.
Fluorinated Materials Development
The presence of three fluorine atoms on the phenyl ring makes this compound useful for developing novel fluorinated materials. These materials can exhibit enhanced thermal stability, chemical resistance, and unique electronic properties, finding potential applications in advanced polymers and electronic components.
Medicinal Chemistry Research
As a building block, it can be employed in the design and synthesis of potential drug candidates. The trifluorophenyl moiety can modulate pharmacokinetic properties such as lipophilicity and metabolic stability, which are critical parameters in drug discovery.
| Molecular weight | 173.09 |
|---|---|
| Empirical formula | C7H2F3NO |
| Assay | 97% |
| Density | 1.429 g/mL at 25 °C |
| Refractive index | n20/D 1.4780 |
Hazard statements
- H226Flammable liquid and vapour
- H300Fatal if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 60 °C / 140 °F |
| Transport (UN / ADR) | UN 1992 3/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 20/21-25-36/37/38 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2,4,5-Trifluorophenyl isocyanate used for?
+
2,4,5-Trifluorophenyl isocyanate is primarily used as a versatile intermediate in organic synthesis for creating complex fluorinated compounds, potentially for applications in materials science, medicinal chemistry, and agrochemical research.
What is the CAS number and molecular formula for 2,4,5-Trifluorophenyl isocyanate?
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The CAS number is 932710-67-3 and the molecular formula is C7H2F3NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2,4,5-Trifluorophenyl isocyanate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should 2,4,5-Trifluorophenyl isocyanate be handled safely?
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This compound is classified as Danger, with hazards including flammability (H226), acute toxicity (H300, H312, H332), and irritation (H315, H319, H335). Handling requires stringent safety measures, including appropriate personal protective equipment such as eyeshields, faceshields, chemical-resistant gloves, and respiratory protection, in a well-ventilated area.
How is 2,4,5-Trifluorophenyl isocyanate packed and shipped?
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2,4,5-Trifluorophenyl isocyanate is packed according to safety regulations for flammable and toxic substances and is exported globally by Tech Serve Solutions. Specific packaging details are available upon request.
How can I request a sample or quote for 2,4,5-Trifluorophenyl isocyanate?
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You can request a sample or a quote by contacting our sales department directly through the website or by calling our customer service line.
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