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Phthaloyl chloride

CAS 88-95-9C6H4-1Chemical Synthesis

Phthaloyl chloride (CAS 88-95-9), with the linear formula C6H4-1,2-(COCl)2 and a molecular weight of 203.02 g/mol, is a reactive organic compound. It serves as a crucial intermediate and building block in various chemical syntheses. Its properties make it valuable in the production of polymers, dyes, and pharmaceuticals.

IUPAC
Phthaloyl dichloride
Synonyms
Phthaloyl dichlorideBenzene-1,2-dicarbonyl dichloride
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Phthaloyl chloride (C6H4-1) — chemical structure, CAS 88-95-9; Chemistry, fine chemical supplied by Tech Serve Solutions
Acid HalidesBuilding BlocksCarbonyl CompoundsChemical SynthesisOrganic Building Blocks
01 /Applications

Organic Synthesis Intermediate

Phthaloyl chloride is widely used as a difunctional electrophile in organic synthesis. It readily reacts with nucleophiles to form cyclic compounds and polymers, facilitating the construction of complex molecular architectures.

Polymerisation Initiator

The reactive nature of phthaloyl chloride allows it to initiate or participate in polymerisation reactions. It is employed in the synthesis of specialty polymers requiring specific structural characteristics derived from its phthaloyl moiety.

Dye and Pigment Precursor

It serves as a key intermediate in the synthesis of various dyes and pigments. Its structure can be incorporated into chromophores to create specific colour properties and enhance dye stability.

Pharmaceutical Intermediate

Phthaloyl chloride is utilised in the multi-step synthesis of certain pharmaceutical compounds. Its reactivity is leveraged to introduce specific functional groups or ring systems necessary for active pharmaceutical ingredients.

02 /Properties
Molecular weight203.02
Linear formulaC6H4-1,2-(COCl)2
Assay≥90%
Boiling point269-271 °C(lit.)
Density1.409 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.568(lit.)n20/D 1.568
Vapour pressure30 mmHg (47 °C)
Melting point6-12 °C(lit.)
Impurities tested~8% anhydride
03 /Safety & handling
GHS hazard pictogram: Corrosive (GHS05)
Corrosive
Danger

Hazard statements

  • H314Causes severe skin burns and eye damage

Precautionary statements

  • P280Wear protective gloves, clothing and eye/face protection
  • P305IF IN EYES
  • P310Immediately call a POISON CENTER or doctor
Protective equipmentFaceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter
Flash point113 °C / 235.4 °F
Transport (UN / ADR)UN 3265 8 / PGII
Water hazard class (WGK, DE)3
Hazard codes (EU)C
Risk statements (R)34
Safety statements (S)26-36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
88-95-9
MDL number
MFCD00000666
PubChem substance
24887504
Beilstein registry
608200
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Phthaloyl chloride used for?

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Phthaloyl chloride is primarily used as an intermediate and building block in organic synthesis, including the production of polymers, dyes, and pharmaceuticals. It is also employed in polymerisation reactions.

What is the CAS number and formula for Phthaloyl chloride?

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The CAS number for Phthaloyl chloride is 88-95-9, and its linear formula is C6H4-1,2-(COCl)2.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Phthaloyl chloride with an assay of ≥90%, containing approximately 8% anhydride. We do not represent this product as USP, BP, or EP grade.

How should Phthaloyl chloride be handled?

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Phthaloyl chloride is a corrosive substance (H314) that causes severe skin burns and eye damage. Handle with extreme care, using full protective equipment including faceshields, gloves, and appropriate respiratory protection (type ABEK filter recommended).

How is Phthaloyl chloride packed and shipped?

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Phthaloyl chloride is shipped as UN 3265, Class 8, Packing Group II. Specific packaging details for export are available upon request.

How can I request a quote or sample?

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To request a quote or a sample of Phthaloyl chloride, please contact our sales team through our website or via the provided contact details.

Need Phthaloyl chloride in a specific grade or volume?