2-Chloro-N6-cyclopentyladenosine
2-Chloro-N6-cyclopentyladenosine (CAS 37739-05-2, C15H20ClN5O4) is a selective A1 adenosine receptor agonist. With a molecular weight of 369.80 g/mol, this compound serves as a valuable tool in pharmacological research. It is frequently employed alongside other adenosine receptor modulators to investigate the distinct functions of A(1), A(2A), and A(3) receptors in biological systems. Primarily used in research settings, it aids in understanding cellular signaling pathways.
- IUPAC
- CCPA

Adenosine Receptor Research
Utilised as a selective A1 adenosine receptor agonist for in vitro and in vivo studies. It aids in differentiating the roles of various adenosine receptor subtypes, particularly A(1), A(2A), and A(3).
Pharmacological Tool
Serves as a key reagent in research aimed at understanding the physiological and pathological roles of adenosine signalling. Its selectivity allows for precise investigation of specific receptor functions.
Drug Discovery and Development
May be used in early-stage drug discovery research targeting pathways modulated by adenosine receptors. Useful in screening and validation of potential therapeutic targets.
| Molecular weight | 369.80 |
|---|---|
| Empirical formula | C15H20ClN5O4 |
| Storage temperature | 2-8°C |
| Application | 2-Chloro-N6-cyclopentyladenosine (CCPA) may be used as an A1 adenosine receptor agonist with high selectivity. CCPA is often used with other adenosine receptor agonists and antagonist to resolve A(1), A(2A) and A(3) receptor functions. These include DPCPX (A(1) receptor antagonist), 4-(2-[7-amino-2-(2-furyl)[1,2,4]triazolo[2,3-α][1,3,5]triazin-5-ylamino]ethyl)phenol (A(2A) receptor antagonist), and 4-[2-[[6-amino-9-(N-ethyl-β-D-ribofuranuronamidosyl)-9H-purin-2-yl]amino]ethyl]benzenepropanoic acid hydrochloride (A(2A) receptor agonist), and Cl-IB-MECA, (A(3)) receptor agonist). |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADORA1(134), ADORA2A(135), ADORA2B(136), ADORA3(140)rat ... Adora1(29290), Adora2a(25369), Adora3(25370) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Chloro-N6-cyclopentyladenosine used for?
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2-Chloro-N6-cyclopentyladenosine (CCPA) is primarily used as a selective A1 adenosine receptor agonist in research. It helps to resolve A(1), A(2A), and A(3) receptor functions when used with other receptor modulators.
What is the CAS number and chemical formula for 2-Chloro-N6-cyclopentyladenosine?
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The CAS number is 37739-05-2 and the empirical formula is C15H20ClN5O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this compound for research purposes. The specific grade and purity are available upon request or via product documentation; it is not supplied as USP, BP, or EP grade.
How should 2-Chloro-N6-cyclopentyladenosine be handled?
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Appropriate personal protective equipment, including eyeshields, gloves, and a type N95 respirator filter, should be used when handling. Refer to the safety data sheet for full handling and hazard information. Classified as WGK 3 in Germany.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 2-Chloro-N6-cyclopentyladenosine, serving researchers worldwide.
How can I request a quote or sample?
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Please contact our sales department via the website or by phone to request a quotation or to arrange for a sample of 2-Chloro-N6-cyclopentyladenosine.
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